Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli

Resistance to one antibiotic can in some cases increase susceptibility to other antibiotics. Here, Podnecky et al. study these collateral responses in E. coli clinical isolates and show that efflux-related resistance mechanisms and relative fitness of the strains are principal contributors to this p...

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Autores principales:	Nicole L. Podnecky, Elizabeth G. A. Fredheim, Julia Kloos, Vidar Sørum, Raul Primicerio, Adam P. Roberts, Daniel E. Rozen, Ørjan Samuelsen, Pål J. Johnsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/161a82352aa642d2845c098a4e132f54
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spelling	oai:doaj.org-article:161a82352aa642d2845c098a4e132f542021-12-02T14:39:10ZConserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli10.1038/s41467-018-06143-y2041-1723https://doaj.org/article/161a82352aa642d2845c098a4e132f542018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06143-yhttps://doaj.org/toc/2041-1723Resistance to one antibiotic can in some cases increase susceptibility to other antibiotics. Here, Podnecky et al. study these collateral responses in E. coli clinical isolates and show that efflux-related resistance mechanisms and relative fitness of the strains are principal contributors to this phenomenon.Nicole L. PodneckyElizabeth G. A. FredheimJulia KloosVidar SørumRaul PrimicerioAdam P. RobertsDaniel E. RozenØrjan SamuelsenPål J. JohnsenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicole L. Podnecky Elizabeth G. A. Fredheim Julia Kloos Vidar Sørum Raul Primicerio Adam P. Roberts Daniel E. Rozen Ørjan Samuelsen Pål J. Johnsen Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
description	Resistance to one antibiotic can in some cases increase susceptibility to other antibiotics. Here, Podnecky et al. study these collateral responses in E. coli clinical isolates and show that efflux-related resistance mechanisms and relative fitness of the strains are principal contributors to this phenomenon.
format	article
author	Nicole L. Podnecky Elizabeth G. A. Fredheim Julia Kloos Vidar Sørum Raul Primicerio Adam P. Roberts Daniel E. Rozen Ørjan Samuelsen Pål J. Johnsen
author_facet	Nicole L. Podnecky Elizabeth G. A. Fredheim Julia Kloos Vidar Sørum Raul Primicerio Adam P. Roberts Daniel E. Rozen Ørjan Samuelsen Pål J. Johnsen
author_sort	Nicole L. Podnecky
title	Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
title_short	Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
title_full	Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
title_fullStr	Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
title_full_unstemmed	Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
title_sort	conserved collateral antibiotic susceptibility networks in diverse clinical strains of escherichia coli
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/161a82352aa642d2845c098a4e132f54
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Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli

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