Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures

Visualising certain organelles and their dynamics is challenging in living cells. Here the authors co-opt selective degradation to label membrane-bound compartments in worm embryos and mammalian cells, revealing membrane topology during cell division.

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Autores principales: Katharina B. Beer, Gholamreza Fazeli, Kristyna Judasova, Linda Irmisch, Jona Causemann, Jörg Mansfeld, Ann M. Wehman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1625e4b9b53c47428c5ed687e5047f73
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spelling oai:doaj.org-article:1625e4b9b53c47428c5ed687e5047f732021-12-02T16:57:55ZDegron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures10.1038/s41467-019-11442-z2041-1723https://doaj.org/article/1625e4b9b53c47428c5ed687e5047f732019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11442-zhttps://doaj.org/toc/2041-1723Visualising certain organelles and their dynamics is challenging in living cells. Here the authors co-opt selective degradation to label membrane-bound compartments in worm embryos and mammalian cells, revealing membrane topology during cell division.Katharina B. BeerGholamreza FazeliKristyna JudasovaLinda IrmischJona CausemannJörg MansfeldAnn M. WehmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katharina B. Beer
Gholamreza Fazeli
Kristyna Judasova
Linda Irmisch
Jona Causemann
Jörg Mansfeld
Ann M. Wehman
Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
description Visualising certain organelles and their dynamics is challenging in living cells. Here the authors co-opt selective degradation to label membrane-bound compartments in worm embryos and mammalian cells, revealing membrane topology during cell division.
format article
author Katharina B. Beer
Gholamreza Fazeli
Kristyna Judasova
Linda Irmisch
Jona Causemann
Jörg Mansfeld
Ann M. Wehman
author_facet Katharina B. Beer
Gholamreza Fazeli
Kristyna Judasova
Linda Irmisch
Jona Causemann
Jörg Mansfeld
Ann M. Wehman
author_sort Katharina B. Beer
title Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
title_short Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
title_full Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
title_fullStr Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
title_full_unstemmed Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
title_sort degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1625e4b9b53c47428c5ed687e5047f73
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