A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

Single-cell studies in solid tissues remain challenging and have benefited from the development of single-nuclei RNA sequencing strategies. Here Lake et al. apply single-nucleus RNA sequencing to human kidney tissues to provide a comprehensive molecular and cellular atlas of the human kidney, with p...

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Autores principales:	Blue B. Lake, Song Chen, Masato Hoshi, Nongluk Plongthongkum, Diane Salamon, Amanda Knoten, Anitha Vijayan, Ramakrishna Venkatesh, Eric H. Kim, Derek Gao, Joseph Gaut, Kun Zhang, Sanjay Jain
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1626047e2e3b4f4c8010bc3a23111c9a
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spelling	oai:doaj.org-article:1626047e2e3b4f4c8010bc3a23111c9a2021-12-02T16:57:06ZA single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys10.1038/s41467-019-10861-22041-1723https://doaj.org/article/1626047e2e3b4f4c8010bc3a23111c9a2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10861-2https://doaj.org/toc/2041-1723Single-cell studies in solid tissues remain challenging and have benefited from the development of single-nuclei RNA sequencing strategies. Here Lake et al. apply single-nucleus RNA sequencing to human kidney tissues to provide a comprehensive molecular and cellular atlas of the human kidney, with potential implications for the understanding of kidney physiology and disease.Blue B. LakeSong ChenMasato HoshiNongluk PlongthongkumDiane SalamonAmanda KnotenAnitha VijayanRamakrishna VenkateshEric H. KimDerek GaoJoseph GautKun ZhangSanjay JainNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Blue B. Lake Song Chen Masato Hoshi Nongluk Plongthongkum Diane Salamon Amanda Knoten Anitha Vijayan Ramakrishna Venkatesh Eric H. Kim Derek Gao Joseph Gaut Kun Zhang Sanjay Jain A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
description	Single-cell studies in solid tissues remain challenging and have benefited from the development of single-nuclei RNA sequencing strategies. Here Lake et al. apply single-nucleus RNA sequencing to human kidney tissues to provide a comprehensive molecular and cellular atlas of the human kidney, with potential implications for the understanding of kidney physiology and disease.
format	article
author	Blue B. Lake Song Chen Masato Hoshi Nongluk Plongthongkum Diane Salamon Amanda Knoten Anitha Vijayan Ramakrishna Venkatesh Eric H. Kim Derek Gao Joseph Gaut Kun Zhang Sanjay Jain
author_facet	Blue B. Lake Song Chen Masato Hoshi Nongluk Plongthongkum Diane Salamon Amanda Knoten Anitha Vijayan Ramakrishna Venkatesh Eric H. Kim Derek Gao Joseph Gaut Kun Zhang Sanjay Jain
author_sort	Blue B. Lake
title	A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
title_short	A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
title_full	A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
title_fullStr	A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
title_full_unstemmed	A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
title_sort	single-nucleus rna-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1626047e2e3b4f4c8010bc3a23111c9a
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A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

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