Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate

It is currently thought that visual pigments in vertebrate photoreceptors are regenerated exclusively through enzymatic cycles. Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of N-ret-PE (N-retinylidene-phosphatidylethanolamine.

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Detalles Bibliográficos
Autores principales: Joanna J. Kaylor, Tongzhou Xu, Norianne T. Ingram, Avian Tsan, Hayk Hakobyan, Gordon L. Fain, Gabriel H. Travis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1627c4ab61794e10891586d484023cf9
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Sumario:It is currently thought that visual pigments in vertebrate photoreceptors are regenerated exclusively through enzymatic cycles. Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of N-ret-PE (N-retinylidene-phosphatidylethanolamine.