Complex regional pain syndrome after severe COVID-19 – A case report

Neurological complications are frequently reported in an intensive care unit (ICU), as a manifestation of a critical systemic illness or of its treatment. On the specific setting of COVID-19 patients, peripheral nerve lesions can have a multiplicity of causes, such as post-infectious neuropathy, pos...

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Autores principales:	Ana Vaz, Andreia Costa, André Pinto, Ana Isabel Silva, Paulo Figueiredo, António Sarmento, Lurdes Santos
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	COVID-19 Critical care Complex regional pain syndrome Peripheral nerve injury Case report Science (General) Q1-390 Social sciences (General) H1-99
Acceso en línea:	https://doaj.org/article/1638639f135e451bbe5a6fa8b39ae1f0
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spelling	oai:doaj.org-article:1638639f135e451bbe5a6fa8b39ae1f02021-12-02T05:03:20ZComplex regional pain syndrome after severe COVID-19 – A case report2405-844010.1016/j.heliyon.2021.e08462https://doaj.org/article/1638639f135e451bbe5a6fa8b39ae1f02021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405844021025652https://doaj.org/toc/2405-8440Neurological complications are frequently reported in an intensive care unit (ICU), as a manifestation of a critical systemic illness or of its treatment. On the specific setting of COVID-19 patients, peripheral nerve lesions can have a multiplicity of causes, such as post-infectious neuropathy, positioning-related neuropathy or iatrogeny. An unusual but potentially disabling complication of any peripheral nerve lesion is Complex Regional Pain Syndrome (CRPS). Although there have been no mechanistic studies assessing how SARS-CoV-2 might directly impact nociception, it is hypothesized that the systemic hyperinflammation seen in severe COVID-19 may contribute to peripheral and central neuronal sensitization, possibly increasing the risk of developing CRPS. This case report highlights the potential hazards and consequences of peripheral nerve injuries on an ICU setting in COVID-19 patients, as well as the importance of a multidisciplinary approach for an early diagnosis and treatment, which are directly related to a better prognosis.Ana VazAndreia CostaAndré PintoAna Isabel SilvaPaulo FigueiredoAntónio SarmentoLurdes SantosElsevierarticleCOVID-19Critical careComplex regional pain syndromePeripheral nerve injuryCase reportScience (General)Q1-390Social sciences (General)H1-99ENHeliyon, Vol 7, Iss 11, Pp e08462- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 Critical care Complex regional pain syndrome Peripheral nerve injury Case report Science (General) Q1-390 Social sciences (General) H1-99
spellingShingle	COVID-19 Critical care Complex regional pain syndrome Peripheral nerve injury Case report Science (General) Q1-390 Social sciences (General) H1-99 Ana Vaz Andreia Costa André Pinto Ana Isabel Silva Paulo Figueiredo António Sarmento Lurdes Santos Complex regional pain syndrome after severe COVID-19 – A case report
description	Neurological complications are frequently reported in an intensive care unit (ICU), as a manifestation of a critical systemic illness or of its treatment. On the specific setting of COVID-19 patients, peripheral nerve lesions can have a multiplicity of causes, such as post-infectious neuropathy, positioning-related neuropathy or iatrogeny. An unusual but potentially disabling complication of any peripheral nerve lesion is Complex Regional Pain Syndrome (CRPS). Although there have been no mechanistic studies assessing how SARS-CoV-2 might directly impact nociception, it is hypothesized that the systemic hyperinflammation seen in severe COVID-19 may contribute to peripheral and central neuronal sensitization, possibly increasing the risk of developing CRPS. This case report highlights the potential hazards and consequences of peripheral nerve injuries on an ICU setting in COVID-19 patients, as well as the importance of a multidisciplinary approach for an early diagnosis and treatment, which are directly related to a better prognosis.
format	article
author	Ana Vaz Andreia Costa André Pinto Ana Isabel Silva Paulo Figueiredo António Sarmento Lurdes Santos
author_facet	Ana Vaz Andreia Costa André Pinto Ana Isabel Silva Paulo Figueiredo António Sarmento Lurdes Santos
author_sort	Ana Vaz
title	Complex regional pain syndrome after severe COVID-19 – A case report
title_short	Complex regional pain syndrome after severe COVID-19 – A case report
title_full	Complex regional pain syndrome after severe COVID-19 – A case report
title_fullStr	Complex regional pain syndrome after severe COVID-19 – A case report
title_full_unstemmed	Complex regional pain syndrome after severe COVID-19 – A case report
title_sort	complex regional pain syndrome after severe covid-19 – a case report
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/1638639f135e451bbe5a6fa8b39ae1f0
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Complex regional pain syndrome after severe COVID-19 – A case report

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