A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells

The Chlamydia pneumoniae adhesin LIPP plays a role in host cell entry and infection. Here, the authors find that LIPP binds to the host plasma membrane and mediates phosphatidylserine translocation, enhancing pathogen internalization without induction of apoptosis.

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Autores principales:	Jan N. Galle, Tim Fechtner, Thorsten Eierhoff, Winfried Römer, Johannes H. Hegemann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1643ac98c9124ac98254b991fe40a290
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spelling	oai:doaj.org-article:1643ac98c9124ac98254b991fe40a2902021-12-02T15:35:58ZA Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells10.1038/s41467-019-12419-82041-1723https://doaj.org/article/1643ac98c9124ac98254b991fe40a2902019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12419-8https://doaj.org/toc/2041-1723The Chlamydia pneumoniae adhesin LIPP plays a role in host cell entry and infection. Here, the authors find that LIPP binds to the host plasma membrane and mediates phosphatidylserine translocation, enhancing pathogen internalization without induction of apoptosis.Jan N. GalleTim FechtnerThorsten EierhoffWinfried RömerJohannes H. HegemannNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jan N. Galle Tim Fechtner Thorsten Eierhoff Winfried Römer Johannes H. Hegemann A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
description	The Chlamydia pneumoniae adhesin LIPP plays a role in host cell entry and infection. Here, the authors find that LIPP binds to the host plasma membrane and mediates phosphatidylserine translocation, enhancing pathogen internalization without induction of apoptosis.
format	article
author	Jan N. Galle Tim Fechtner Thorsten Eierhoff Winfried Römer Johannes H. Hegemann
author_facet	Jan N. Galle Tim Fechtner Thorsten Eierhoff Winfried Römer Johannes H. Hegemann
author_sort	Jan N. Galle
title	A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
title_short	A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
title_full	A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
title_fullStr	A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
title_full_unstemmed	A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
title_sort	chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1643ac98c9124ac98254b991fe40a290
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A Chlamydia pneumoniae adhesin induces phosphatidylserine exposure on host cells

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