A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.

<h4>Objective</h4>To determine psychometric properties of the PROMIS-10 and Standard Stroke Question Set (by International Consortium for Health Outcome Measures) presented as a new 15-item Patient Related Outcome (PRO), for patients with: acquired Brain Injury (ABI), Multiple sclerosis...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ben Carter, Chloe Hayes, Alexander Smith, Anna Pennington, Michelle Price, Owen Pearson, Silia Vitoratou, Jonathan Hewitt
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/16496adcd7dc43da84b22d7ebe6fb3f3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:16496adcd7dc43da84b22d7ebe6fb3f3
record_format	dspace
spelling	oai:doaj.org-article:16496adcd7dc43da84b22d7ebe6fb3f32021-12-02T20:03:56ZA single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.1932-620310.1371/journal.pone.0251484https://doaj.org/article/16496adcd7dc43da84b22d7ebe6fb3f32021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251484https://doaj.org/toc/1932-6203<h4>Objective</h4>To determine psychometric properties of the PROMIS-10 and Standard Stroke Question Set (by International Consortium for Health Outcome Measures) presented as a new 15-item Patient Related Outcome (PRO), for patients with: acquired Brain Injury (ABI), Multiple sclerosis (MS) and Parkinson's disease (PD).<h4>Methods</h4>In an eight centre, UK wide, cross-sectional study we approached patients during their routine follow-up to complete: a disease-specific instrument (European Brain Injury Questionnaire, Multiple Sclerosis Impact Scale, and Parkinson's disease questionnaire); General Health questionnaire with a Quality of life measure (EQ-5D); and PRO. We validated the PRO using factor analysis to define the latent construct domains, then calculated the internal consistency (Cronbach's-α), and construct validity (correlation).<h4>Results</h4>There were 340 patients with ABI (N = 91, median age = 55.1, 41% female), MS (N = 99, age = 58.9, 69%) and PD (N = 150, age = 74.5, 40%). Factor analysis suggested the PRO offered three domains of: physical health; functionality-capacity and mental health. All factors correlated strongly with the three disease-specific instruments, and the overall PRO had a large correlation with the EQ-5D (correlation>0.8) offering good construct validity and excellent internal consistency (∝>0.89).<h4>Interpretation</h4>The PRO offered promising psychometric properties and could be used in place of disease specific questionnaires for patients with ABI, MS, and PD. The PRO has three construct domains, describing patients': mental health; physical health; and functional-capacity, and may be used in routine clinical practice. The PRO offered both relevance to each of the three separate neurological conditions and generalisability across all the conditions, increasing its utility.Ben CarterChloe HayesAlexander SmithAnna PenningtonMichelle PriceOwen PearsonSilia VitoratouJonathan HewittPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0251484 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ben Carter Chloe Hayes Alexander Smith Anna Pennington Michelle Price Owen Pearson Silia Vitoratou Jonathan Hewitt A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
description	<h4>Objective</h4>To determine psychometric properties of the PROMIS-10 and Standard Stroke Question Set (by International Consortium for Health Outcome Measures) presented as a new 15-item Patient Related Outcome (PRO), for patients with: acquired Brain Injury (ABI), Multiple sclerosis (MS) and Parkinson's disease (PD).<h4>Methods</h4>In an eight centre, UK wide, cross-sectional study we approached patients during their routine follow-up to complete: a disease-specific instrument (European Brain Injury Questionnaire, Multiple Sclerosis Impact Scale, and Parkinson's disease questionnaire); General Health questionnaire with a Quality of life measure (EQ-5D); and PRO. We validated the PRO using factor analysis to define the latent construct domains, then calculated the internal consistency (Cronbach's-α), and construct validity (correlation).<h4>Results</h4>There were 340 patients with ABI (N = 91, median age = 55.1, 41% female), MS (N = 99, age = 58.9, 69%) and PD (N = 150, age = 74.5, 40%). Factor analysis suggested the PRO offered three domains of: physical health; functionality-capacity and mental health. All factors correlated strongly with the three disease-specific instruments, and the overall PRO had a large correlation with the EQ-5D (correlation>0.8) offering good construct validity and excellent internal consistency (∝>0.89).<h4>Interpretation</h4>The PRO offered promising psychometric properties and could be used in place of disease specific questionnaires for patients with ABI, MS, and PD. The PRO has three construct domains, describing patients': mental health; physical health; and functional-capacity, and may be used in routine clinical practice. The PRO offered both relevance to each of the three separate neurological conditions and generalisability across all the conditions, increasing its utility.
format	article
author	Ben Carter Chloe Hayes Alexander Smith Anna Pennington Michelle Price Owen Pearson Silia Vitoratou Jonathan Hewitt
author_facet	Ben Carter Chloe Hayes Alexander Smith Anna Pennington Michelle Price Owen Pearson Silia Vitoratou Jonathan Hewitt
author_sort	Ben Carter
title	A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
title_short	A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
title_full	A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
title_fullStr	A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
title_full_unstemmed	A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.
title_sort	single patient reported outcome measure for acquired brain injury, multiple sclerosis & parkinson's disease.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/16496adcd7dc43da84b22d7ebe6fb3f3
work_keys_str_mv	AT bencarter asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT chloehayes asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT alexandersmith asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT annapennington asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT michelleprice asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT owenpearson asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT siliavitoratou asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT jonathanhewitt asinglepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT bencarter singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT chloehayes singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT alexandersmith singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT annapennington singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT michelleprice singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT owenpearson singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT siliavitoratou singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease AT jonathanhewitt singlepatientreportedoutcomemeasureforacquiredbraininjurymultiplesclerosisparkinsonsdisease
_version_	1718375587197747200

A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease.

Ejemplares similares