Lung cancer in women
Raúl Barrera-Rodriguez,1 Jorge Morales-Fuentes2 1Biochemistry and Environmental Medicine Laboratory, National Institute of Respiratory Disease, 2Lung Cancer Medical Service, National Institute of Respiratory Disease, Tlalpan, Mexico City, Distrito Federal, Mexico Both authors contribu...
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Dove Medical Press
2012
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oai:doaj.org-article:164d488bab4d4d409a089c2f56ea90ff2021-12-02T01:36:30ZLung cancer in women1179-2728https://doaj.org/article/164d488bab4d4d409a089c2f56ea90ff2012-12-01T00:00:00Zhttp://www.dovepress.com/lung-cancer-in-women-a11770https://doaj.org/toc/1179-2728Raúl Barrera-Rodriguez,1 Jorge Morales-Fuentes2 1Biochemistry and Environmental Medicine Laboratory, National Institute of Respiratory Disease, 2Lung Cancer Medical Service, National Institute of Respiratory Disease, Tlalpan, Mexico City, Distrito Federal, Mexico Both authors contributed equally to this workAbstract: Recent biological advances in tumor research provide clear evidence that lung cancer in females is different from that in males. These differences appear to have a direct impact on the clinical presentation, histology, and outcomes of lung cancer. Women are more likely to present with lung adenocarcinoma, tend to receive a diagnosis at an earlier age, and are more likely to be diagnosed with localized disease. Women may also be more predisposed to molecular aberrations resulting from the carcinogenic effects of tobacco, but do not appear to be more susceptible than men to developing lung cancer. The gender differences found in female lung cancer make it mandatory that gender stratification is used in clinical trials in order to improve the survival rates of patients with lung cancer.Keywords: lung cancer, adenocarcinoma, women, genetic susceptibility, genetic differences, tobaccoBarrera-Rodriguez RMorales-Fuentes JDove Medical PressarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENLung Cancer: Targets and Therapy, Vol 2012, Iss default, Pp 79-89 (2012) |
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DOAJ |
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EN |
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Barrera-Rodriguez R Morales-Fuentes J Lung cancer in women |
| description |
Raúl Barrera-Rodriguez,1 Jorge Morales-Fuentes2 1Biochemistry and Environmental Medicine Laboratory, National Institute of Respiratory Disease, 2Lung Cancer Medical Service, National Institute of Respiratory Disease, Tlalpan, Mexico City, Distrito Federal, Mexico Both authors contributed equally to this workAbstract: Recent biological advances in tumor research provide clear evidence that lung cancer in females is different from that in males. These differences appear to have a direct impact on the clinical presentation, histology, and outcomes of lung cancer. Women are more likely to present with lung adenocarcinoma, tend to receive a diagnosis at an earlier age, and are more likely to be diagnosed with localized disease. Women may also be more predisposed to molecular aberrations resulting from the carcinogenic effects of tobacco, but do not appear to be more susceptible than men to developing lung cancer. The gender differences found in female lung cancer make it mandatory that gender stratification is used in clinical trials in order to improve the survival rates of patients with lung cancer.Keywords: lung cancer, adenocarcinoma, women, genetic susceptibility, genetic differences, tobacco |
| format |
article |
| author |
Barrera-Rodriguez R Morales-Fuentes J |
| author_facet |
Barrera-Rodriguez R Morales-Fuentes J |
| author_sort |
Barrera-Rodriguez R |
| title |
Lung cancer in women |
| title_short |
Lung cancer in women |
| title_full |
Lung cancer in women |
| title_fullStr |
Lung cancer in women |
| title_full_unstemmed |
Lung cancer in women |
| title_sort |
lung cancer in women |
| publisher |
Dove Medical Press |
| publishDate |
2012 |
| url |
https://doaj.org/article/164d488bab4d4d409a089c2f56ea90ff |
| work_keys_str_mv |
AT barrerarodriguezr lungcancerinwomen AT moralesfuentesj lungcancerinwomen |
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1718402942559584256 |