Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection.

<h4>Background</h4>Type III interferon, or interferon lambda (IFNλ) is a crucial antiviral cytokine induced by influenza infection. While IFNλ is important for anti-viral host defense, published data demonstrate that IFNλ is pathogenic during influenza/bacterial super-infection. It is kn...

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Autores principales: Helen E Rich, Danielle Antos, Collin C McCourt, Wen Quan Zheng, Louis J Devito, Kevin J McHugh, Radha Gopal, Jieru Wang, John F Alcorn
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/164f797b44ad4746969acad593a6ba44
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