Mutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells

Abstract Missense mutations of TP53 are extremely common, and mutant p53 accumulation and gain-of-function play crucial roles in human ovarian cancer. Here, we investigated the role of mutant p53 in cell migration and invasion as well as its underlying molecular mechanisms in human ovarian cancer ce...

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Autores principales: Ji-Hye Ahn, Tae Jin Kim, Jae Ho Lee, Jung-Hye Choi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1653a13b3dd7420092575dd7043c22ec
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