Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment

The article is devoted to the estimation of morphological changes in liver of experimental animals with acute hepatic failure caused by toxic injury of liver under the influence of xenotransplantation of culture of cryopreserved cells of liver and isolated cryopreserved neonatal hepatocytes. It was...

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Autores principales:	S. A. Lepekhova, O. A. Goldberg, K. A. Apartsin, M. V. Prokopyev
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	acute hepatic failure cells of liver transplantation morphology Science Q
Acceso en línea:	https://doaj.org/article/165cea0b74a442f5a58456bf05252a2b
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spelling	oai:doaj.org-article:165cea0b74a442f5a58456bf05252a2b2021-11-23T06:14:27ZDifferentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment2541-94202587-9596https://doaj.org/article/165cea0b74a442f5a58456bf05252a2b2013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1542https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article is devoted to the estimation of morphological changes in liver of experimental animals with acute hepatic failure caused by toxic injury of liver under the influence of xenotransplantation of culture of cryopreserved cells of liver and isolated cryopreserved neonatal hepatocytes. It was determined that undamaged hepatocytes with simultaneous decrease of number of vacuolated cells, preservation. of beam structure, decrease of fat insertions prevailed in the liver of animals with xenotransplantation of culture of cryopreserved cells of liver to the 6th day. At the transplantation of isolated neonatal hepatocytes number of hepatocytes with undamaged structure decreased and number of damaged hepatocytes increased. Thus, cultivated cryopreserved cells of liver are the cells of choice of correction of acute toxic liver injury.S. A. LepekhovaO. A. GoldbergK. A. ApartsinM. V. ProkopyevScientific Сentre for Family Health and Human Reproduction Problemsarticleacute hepatic failurecells of livertransplantationmorphologyScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(1), Pp 128-132 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	acute hepatic failure cells of liver transplantation morphology Science Q
spellingShingle	acute hepatic failure cells of liver transplantation morphology Science Q S. A. Lepekhova O. A. Goldberg K. A. Apartsin M. V. Prokopyev Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
description	The article is devoted to the estimation of morphological changes in liver of experimental animals with acute hepatic failure caused by toxic injury of liver under the influence of xenotransplantation of culture of cryopreserved cells of liver and isolated cryopreserved neonatal hepatocytes. It was determined that undamaged hepatocytes with simultaneous decrease of number of vacuolated cells, preservation. of beam structure, decrease of fat insertions prevailed in the liver of animals with xenotransplantation of culture of cryopreserved cells of liver to the 6th day. At the transplantation of isolated neonatal hepatocytes number of hepatocytes with undamaged structure decreased and number of damaged hepatocytes increased. Thus, cultivated cryopreserved cells of liver are the cells of choice of correction of acute toxic liver injury.
format	article
author	S. A. Lepekhova O. A. Goldberg K. A. Apartsin M. V. Prokopyev
author_facet	S. A. Lepekhova O. A. Goldberg K. A. Apartsin M. V. Prokopyev
author_sort	S. A. Lepekhova
title	Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
title_short	Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
title_full	Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
title_fullStr	Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
title_full_unstemmed	Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment
title_sort	differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. morphological basis of choosing the way of treatment
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/165cea0b74a442f5a58456bf05252a2b
work_keys_str_mv	AT salepekhova differentiatedapproachtocellcorrectionofacutehepaticfailureattheacutetoxicinjurymorphologicalbasisofchoosingthewayoftreatment AT oagoldberg differentiatedapproachtocellcorrectionofacutehepaticfailureattheacutetoxicinjurymorphologicalbasisofchoosingthewayoftreatment AT kaapartsin differentiatedapproachtocellcorrectionofacutehepaticfailureattheacutetoxicinjurymorphologicalbasisofchoosingthewayoftreatment AT mvprokopyev differentiatedapproachtocellcorrectionofacutehepaticfailureattheacutetoxicinjurymorphologicalbasisofchoosingthewayoftreatment
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Differentiated approach to cell correction of acute hepatic failure at the acute toxic injury. Morphological basis of choosing the way of treatment

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