AIF downregulation and its interaction with STK3 in renal cell carcinoma.

Apoptosis-inducing factor (AIF) plays a crucial role in caspase-independent programmed cell death by triggering chromatin condensation and DNA fragmentation. Therefore, it might be involved in cell homeostasis and tumor development. In this study, we report significant AIF downregulation in the majo...

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Autores principales: Shengqiang Xu, Hongjin Wu, Huan Nie, Lei Yue, Huadong Jiang, Sheng Xiao, Yu Li
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/165cebf6a2614a30b53fb8da51d20722
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