Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

Mycobacteria are naturally resilient, and mycobacterial infections are notoriously difficult to treat with antibiotics, with biofilm formation being the main factor complicating the successful treatment of tuberculosis (TB). The present study shows that nontuberculous Mycobacterium marinum

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Autores principales: Kirsi Savijoki, Henna Myllymäki, Hanna Luukinen, Lauri Paulamäki, Leena-Maija Vanha-aho, Aleksandra Svorjova, Ilkka Miettinen, Adyary Fallarero, Teemu O. Ihalainen, Jari Yli-Kauhaluoma, Tuula A. Nyman, Mataleena Parikka
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Microbiology
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Acceso en línea:https://doaj.org/article/16725e605e6c4de2aaa60e074a5c7d62
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spelling oai:doaj.org-article:16725e605e6c4de2aaa60e074a5c7d622021-12-02T18:48:30ZSurface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence2379-507710.1128/mSystems.00500-21https://doaj.org/article/16725e605e6c4de2aaa60e074a5c7d622021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00500-21https://doaj.org/toc/2379-5077 Mycobacteria are naturally resilient, and mycobacterial infections are notoriously difficult to treat with antibiotics, with biofilm formation being the main factor complicating the successful treatment of tuberculosis (TB). The present study shows that nontuberculous Mycobacterium marinumKirsi SavijokiHenna MyllymäkiHanna LuukinenLauri PaulamäkiLeena-Maija Vanha-ahoAleksandra SvorjovaIlkka MiettinenAdyary FallareroTeemu O. IhalainenJari Yli-KauhaluomaTuula A. NymanMataleena ParikkaAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Kirsi Savijoki
Henna Myllymäki
Hanna Luukinen
Lauri Paulamäki
Leena-Maija Vanha-aho
Aleksandra Svorjova
Ilkka Miettinen
Adyary Fallarero
Teemu O. Ihalainen
Jari Yli-Kauhaluoma
Tuula A. Nyman
Mataleena Parikka
Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
description Mycobacteria are naturally resilient, and mycobacterial infections are notoriously difficult to treat with antibiotics, with biofilm formation being the main factor complicating the successful treatment of tuberculosis (TB). The present study shows that nontuberculous Mycobacterium marinum
format article
author Kirsi Savijoki
Henna Myllymäki
Hanna Luukinen
Lauri Paulamäki
Leena-Maija Vanha-aho
Aleksandra Svorjova
Ilkka Miettinen
Adyary Fallarero
Teemu O. Ihalainen
Jari Yli-Kauhaluoma
Tuula A. Nyman
Mataleena Parikka
author_facet Kirsi Savijoki
Henna Myllymäki
Hanna Luukinen
Lauri Paulamäki
Leena-Maija Vanha-aho
Aleksandra Svorjova
Ilkka Miettinen
Adyary Fallarero
Teemu O. Ihalainen
Jari Yli-Kauhaluoma
Tuula A. Nyman
Mataleena Parikka
author_sort Kirsi Savijoki
title Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
title_short Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
title_full Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
title_fullStr Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
title_full_unstemmed Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
title_sort surface-shaving proteomics of mycobacterium marinum identifies biofilm subtype-specific changes affecting virulence, tolerance, and persistence
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/16725e605e6c4de2aaa60e074a5c7d62
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