A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphos...
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Nature Portfolio
2016
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oai:doaj.org-article:168360a90d9b4e20887ce23073c640172021-12-02T16:56:45ZA developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts10.1038/ncomms110692041-1723https://doaj.org/article/168360a90d9b4e20887ce23073c640172016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11069https://doaj.org/toc/2041-1723How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphosis.Hibiki Vincent TanakaNathaniel Chuen Yin NgZhan Yang YuMartin Miguel Casco-RoblesFumiaki MaruoPanagiotis A. TsonisChikafumi ChibaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Hibiki Vincent Tanaka Nathaniel Chuen Yin Ng Zhan Yang Yu Martin Miguel Casco-Robles Fumiaki Maruo Panagiotis A. Tsonis Chikafumi Chiba A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
description |
How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphosis. |
format |
article |
author |
Hibiki Vincent Tanaka Nathaniel Chuen Yin Ng Zhan Yang Yu Martin Miguel Casco-Robles Fumiaki Maruo Panagiotis A. Tsonis Chikafumi Chiba |
author_facet |
Hibiki Vincent Tanaka Nathaniel Chuen Yin Ng Zhan Yang Yu Martin Miguel Casco-Robles Fumiaki Maruo Panagiotis A. Tsonis Chikafumi Chiba |
author_sort |
Hibiki Vincent Tanaka |
title |
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
title_short |
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
title_full |
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
title_fullStr |
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
title_full_unstemmed |
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
title_sort |
developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/168360a90d9b4e20887ce23073c64017 |
work_keys_str_mv |
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1718382726323634176 |