A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts

How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphos...

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Autores principales: Hibiki Vincent Tanaka, Nathaniel Chuen Yin Ng, Zhan Yang Yu, Martin Miguel Casco-Robles, Fumiaki Maruo, Panagiotis A. Tsonis, Chikafumi Chiba
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/168360a90d9b4e20887ce23073c64017
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spelling oai:doaj.org-article:168360a90d9b4e20887ce23073c640172021-12-02T16:56:45ZA developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts10.1038/ncomms110692041-1723https://doaj.org/article/168360a90d9b4e20887ce23073c640172016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11069https://doaj.org/toc/2041-1723How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphosis.Hibiki Vincent TanakaNathaniel Chuen Yin NgZhan Yang YuMartin Miguel Casco-RoblesFumiaki MaruoPanagiotis A. TsonisChikafumi ChibaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hibiki Vincent Tanaka
Nathaniel Chuen Yin Ng
Zhan Yang Yu
Martin Miguel Casco-Robles
Fumiaki Maruo
Panagiotis A. Tsonis
Chikafumi Chiba
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
description How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphosis.
format article
author Hibiki Vincent Tanaka
Nathaniel Chuen Yin Ng
Zhan Yang Yu
Martin Miguel Casco-Robles
Fumiaki Maruo
Panagiotis A. Tsonis
Chikafumi Chiba
author_facet Hibiki Vincent Tanaka
Nathaniel Chuen Yin Ng
Zhan Yang Yu
Martin Miguel Casco-Robles
Fumiaki Maruo
Panagiotis A. Tsonis
Chikafumi Chiba
author_sort Hibiki Vincent Tanaka
title A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
title_short A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
title_full A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
title_fullStr A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
title_full_unstemmed A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
title_sort developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/168360a90d9b4e20887ce23073c64017
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