Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells

Abstract Background High temperature requirement A (HtrA) is an active serine protease secreted by the group-I carcinogen Helicobacter pylori (H. pylori). The human cell adhesion protein and tumor suppressor E-cadherin (hCdh1) expressed on the surface of gastric epithelial cells was identified as th...

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Main Authors: Sabine Bernegger, Robert Vidmar, Marko Fonovic, Gernot Posselt, Boris Turk, Silja Wessler
Format: article
Language:EN
Published: BMC 2021
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Online Access:https://doaj.org/article/16a0e2b933244d749b94d26a156c2a11
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