Melanoma: Staging and Follow-Up

Cancer staging is the process determining to which extent a cancer has spread and where it is located in the body. A thorough staging is of utmost importance, not only because it provides the most accurate prognostic estimation, but also because several crucial decisions, such as the treatment choi...

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Autores principales: Chryssoula Papageorgiou, Zoe Apalla, Sofia-Magdalini Manoli, Konstantinos Lallas, Efstratios Vakirlis, Aimilios Lallas
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Lenguaje:EN
Publicado: Mattioli1885 2021
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Acceso en línea:https://doaj.org/article/16a49f013e7d4ebeae8ac1918b14e2c7
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spelling oai:doaj.org-article:16a49f013e7d4ebeae8ac1918b14e2c72021-11-17T08:27:40ZMelanoma: Staging and Follow-Up10.5826/dpc.11S1a162S2160-9381https://doaj.org/article/16a49f013e7d4ebeae8ac1918b14e2c72021-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1795https://doaj.org/toc/2160-9381 Cancer staging is the process determining to which extent a cancer has spread and where it is located in the body. A thorough staging is of utmost importance, not only because it provides the most accurate prognostic estimation, but also because several crucial decisions, such as the treatment choice and the follow-up strategy, vary according to the tumor’s stage. The current staging system for melanoma is based on the 8th edition of TNM classification issued by the American Joint Committee on Cancer (AJCC) in 2017. It includes a clinical and a pathological staging, both consisting of 5 stages (0-IV). The stage of a melanoma is determined by several factors, among which the Breslow thickness, the pathological presence or absence of ulceration in the primary tumor, the presence and the number of tumor-involved regional lymph nodes, the presence or absence of in-transit, satellite and/or microsatellite metastases, and the presence of distant metastases. Following melanoma diagnosis, an accurate medical workup, in line with the stage and the physical examination, should be performed. A continuous patient monitoring is fundamental to detect a potential relapse or a second primary melanoma and should be lifelong. However, there is still no universally adopted follow-up strategy program and different follow-up schemes have been suggested. Future prospective studies are needed to evaluate different follow-up protocols according to the adopted therapy, as novel recent therapies (targeted and immunotherapies) are being increasingly used. Chryssoula PapageorgiouZoe ApallaSofia-Magdalini ManoliKonstantinos LallasEfstratios VakirlisAimilios LallasMattioli1885articleMelanomastagingfollow-upDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 11, Iss S1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Melanoma
staging
follow-up
Dermatology
RL1-803
spellingShingle Melanoma
staging
follow-up
Dermatology
RL1-803
Chryssoula Papageorgiou
Zoe Apalla
Sofia-Magdalini Manoli
Konstantinos Lallas
Efstratios Vakirlis
Aimilios Lallas
Melanoma: Staging and Follow-Up
description Cancer staging is the process determining to which extent a cancer has spread and where it is located in the body. A thorough staging is of utmost importance, not only because it provides the most accurate prognostic estimation, but also because several crucial decisions, such as the treatment choice and the follow-up strategy, vary according to the tumor’s stage. The current staging system for melanoma is based on the 8th edition of TNM classification issued by the American Joint Committee on Cancer (AJCC) in 2017. It includes a clinical and a pathological staging, both consisting of 5 stages (0-IV). The stage of a melanoma is determined by several factors, among which the Breslow thickness, the pathological presence or absence of ulceration in the primary tumor, the presence and the number of tumor-involved regional lymph nodes, the presence or absence of in-transit, satellite and/or microsatellite metastases, and the presence of distant metastases. Following melanoma diagnosis, an accurate medical workup, in line with the stage and the physical examination, should be performed. A continuous patient monitoring is fundamental to detect a potential relapse or a second primary melanoma and should be lifelong. However, there is still no universally adopted follow-up strategy program and different follow-up schemes have been suggested. Future prospective studies are needed to evaluate different follow-up protocols according to the adopted therapy, as novel recent therapies (targeted and immunotherapies) are being increasingly used.
format article
author Chryssoula Papageorgiou
Zoe Apalla
Sofia-Magdalini Manoli
Konstantinos Lallas
Efstratios Vakirlis
Aimilios Lallas
author_facet Chryssoula Papageorgiou
Zoe Apalla
Sofia-Magdalini Manoli
Konstantinos Lallas
Efstratios Vakirlis
Aimilios Lallas
author_sort Chryssoula Papageorgiou
title Melanoma: Staging and Follow-Up
title_short Melanoma: Staging and Follow-Up
title_full Melanoma: Staging and Follow-Up
title_fullStr Melanoma: Staging and Follow-Up
title_full_unstemmed Melanoma: Staging and Follow-Up
title_sort melanoma: staging and follow-up
publisher Mattioli1885
publishDate 2021
url https://doaj.org/article/16a49f013e7d4ebeae8ac1918b14e2c7
work_keys_str_mv AT chryssoulapapageorgiou melanomastagingandfollowup
AT zoeapalla melanomastagingandfollowup
AT sofiamagdalinimanoli melanomastagingandfollowup
AT konstantinoslallas melanomastagingandfollowup
AT efstratiosvakirlis melanomastagingandfollowup
AT aimilioslallas melanomastagingandfollowup
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