Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
Cortical thickness is asymmetric, and cortical thinning occurs with age and in disease. Here the authors investigate if both cortices thin at the same rate or if the thicker hemisphere declines faster in aging and in Alzheimer’s disease.
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Nature Portfolio
2021
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| Acceso en línea: | https://doaj.org/article/16a87559415346a88b0be38f10fab5c6 |
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oai:doaj.org-article:16a87559415346a88b0be38f10fab5c62021-12-02T14:06:16ZAsymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease10.1038/s41467-021-21057-y2041-1723https://doaj.org/article/16a87559415346a88b0be38f10fab5c62021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21057-yhttps://doaj.org/toc/2041-1723Cortical thickness is asymmetric, and cortical thinning occurs with age and in disease. Here the authors investigate if both cortices thin at the same rate or if the thicker hemisphere declines faster in aging and in Alzheimer’s disease.James M. RoeDidac Vidal-PiñeiroØystein SørensenAndreas M. BrandmaierSandra DüzelHector A. GonzalezRogier A. KievitEthan KnightsSimone KühnUlman LindenbergerAthanasia M. MowinckelLars NybergDenise C. ParkSara PudasMelissa M. RundleKristine B. WalhovdAnders M. FjellRené WesterhausenThe Australian Imaging Biomarkers and Lifestyle Flagship Study of AgeingNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
| institution |
DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q James M. Roe Didac Vidal-Piñeiro Øystein Sørensen Andreas M. Brandmaier Sandra Düzel Hector A. Gonzalez Rogier A. Kievit Ethan Knights Simone Kühn Ulman Lindenberger Athanasia M. Mowinckel Lars Nyberg Denise C. Park Sara Pudas Melissa M. Rundle Kristine B. Walhovd Anders M. Fjell René Westerhausen The Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| description |
Cortical thickness is asymmetric, and cortical thinning occurs with age and in disease. Here the authors investigate if both cortices thin at the same rate or if the thicker hemisphere declines faster in aging and in Alzheimer’s disease. |
| format |
article |
| author |
James M. Roe Didac Vidal-Piñeiro Øystein Sørensen Andreas M. Brandmaier Sandra Düzel Hector A. Gonzalez Rogier A. Kievit Ethan Knights Simone Kühn Ulman Lindenberger Athanasia M. Mowinckel Lars Nyberg Denise C. Park Sara Pudas Melissa M. Rundle Kristine B. Walhovd Anders M. Fjell René Westerhausen The Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing |
| author_facet |
James M. Roe Didac Vidal-Piñeiro Øystein Sørensen Andreas M. Brandmaier Sandra Düzel Hector A. Gonzalez Rogier A. Kievit Ethan Knights Simone Kühn Ulman Lindenberger Athanasia M. Mowinckel Lars Nyberg Denise C. Park Sara Pudas Melissa M. Rundle Kristine B. Walhovd Anders M. Fjell René Westerhausen The Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing |
| author_sort |
James M. Roe |
| title |
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| title_short |
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| title_full |
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| title_fullStr |
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| title_full_unstemmed |
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease |
| title_sort |
asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in alzheimer’s disease |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/16a87559415346a88b0be38f10fab5c6 |
| work_keys_str_mv |
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