Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis

Background: Bovine campylobacteriosis is a venereal disease due to infection with Campylobacter fetus venerealis. It causes mainly reproductive failures that lead to considerable economic losses. Objective: To perform a histopathological description of the mucosa from reproductive organs of heifers...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	María Giobergia, Marcela Herrera, Miriam Teruel, Belén Riccio, Maria Catena
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2019
Materias:	campylobacter fetus venerealis cattle heifers histopathology lymphocytic inflammation oviduct postmating infection uterus vagina venereal disease Animal culture SF1-1100
Acceso en línea:	https://doaj.org/article/16aabc435177482cad7cdd556f61a23f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:16aabc435177482cad7cdd556f61a23f
record_format	dspace
spelling	oai:doaj.org-article:16aabc435177482cad7cdd556f61a23f2021-12-01T15:27:55ZHistopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis2256-295810.17533/udea.rccp.v33n1a05https://doaj.org/article/16aabc435177482cad7cdd556f61a23f2019-11-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/rccp/article/view/340411https://doaj.org/toc/2256-2958Background: Bovine campylobacteriosis is a venereal disease due to infection with Campylobacter fetus venerealis. It causes mainly reproductive failures that lead to considerable economic losses. Objective: To perform a histopathological description of the mucosa from reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis. Methods: Twelve 15-18-months-old Aberdeen Angus heifers were treated for estrous synchronization and exposed to natural breeding. They were then randomly divided into two groups: group A (n=9) was inoculated with C. fetus venerealis; group B (n=3, control) was inoculated with a placebo. Ultrasonography was performed at days 29, 38, and 42 post-breeding, and plasmatic progesterone levels were quantified using ELISA to confirm pregnancies. Animals in group A with plasma progesterone levels below 1 ng/mL and/or diagnosed as non-pregnant were further divided into three subgroups: A1 (n=4), euthanized at day 30 post-breeding; A2 (n=3), euthanized at day 40 post-breeding and A3 (n=2), euthanized at day 55 postbreeding. Heifers from group B, all diagnosed as pregnant, were euthanized each at day 30, 40, and 55 days post-breeding as well. Histological sections from every group were taken from oviducts, uterus, and vagina. Results: Lymphocytic inflammation was the most common lesion in all infected heifers. Trophoblast cells were found in the non-pregnant heifers euthanized at days 40, and 55 post-breeding. The inflammatory process with the presence of lymphoid cells probably altered the balance in the activity of maternal lymphoid cells, as well as gene expression of the trophoblast, finally affecting the embryo survival. Conclusion: This work contributes to the understanding of the histopathological process involved in post-mating infection of Campylobacter fetus bovine.María GiobergiaMarcela HerreraMiriam TeruelBelén RiccioMaria CatenaUniversidad de Antioquiaarticlecampylobacter fetus venerealiscattleheifershistopathologylymphocytic inflammationoviductpostmating infectionuterusvaginavenereal diseaseAnimal cultureSF1-1100ENRevista Colombiana de Ciencias Pecuarias, Vol 33, Iss 3, Pp 149-158 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	campylobacter fetus venerealis cattle heifers histopathology lymphocytic inflammation oviduct postmating infection uterus vagina venereal disease Animal culture SF1-1100
spellingShingle	campylobacter fetus venerealis cattle heifers histopathology lymphocytic inflammation oviduct postmating infection uterus vagina venereal disease Animal culture SF1-1100 María Giobergia Marcela Herrera Miriam Teruel Belén Riccio Maria Catena Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
description	Background: Bovine campylobacteriosis is a venereal disease due to infection with Campylobacter fetus venerealis. It causes mainly reproductive failures that lead to considerable economic losses. Objective: To perform a histopathological description of the mucosa from reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis. Methods: Twelve 15-18-months-old Aberdeen Angus heifers were treated for estrous synchronization and exposed to natural breeding. They were then randomly divided into two groups: group A (n=9) was inoculated with C. fetus venerealis; group B (n=3, control) was inoculated with a placebo. Ultrasonography was performed at days 29, 38, and 42 post-breeding, and plasmatic progesterone levels were quantified using ELISA to confirm pregnancies. Animals in group A with plasma progesterone levels below 1 ng/mL and/or diagnosed as non-pregnant were further divided into three subgroups: A1 (n=4), euthanized at day 30 post-breeding; A2 (n=3), euthanized at day 40 post-breeding and A3 (n=2), euthanized at day 55 postbreeding. Heifers from group B, all diagnosed as pregnant, were euthanized each at day 30, 40, and 55 days post-breeding as well. Histological sections from every group were taken from oviducts, uterus, and vagina. Results: Lymphocytic inflammation was the most common lesion in all infected heifers. Trophoblast cells were found in the non-pregnant heifers euthanized at days 40, and 55 post-breeding. The inflammatory process with the presence of lymphoid cells probably altered the balance in the activity of maternal lymphoid cells, as well as gene expression of the trophoblast, finally affecting the embryo survival. Conclusion: This work contributes to the understanding of the histopathological process involved in post-mating infection of Campylobacter fetus bovine.
format	article
author	María Giobergia Marcela Herrera Miriam Teruel Belén Riccio Maria Catena
author_facet	María Giobergia Marcela Herrera Miriam Teruel Belén Riccio Maria Catena
author_sort	María Giobergia
title	Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
title_short	Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
title_full	Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
title_fullStr	Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
title_full_unstemmed	Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis
title_sort	histopathologic characterization of the reproductive organs of heifers experimentally infected with campylobacter fetus venerealis
publisher	Universidad de Antioquia
publishDate	2019
url	https://doaj.org/article/16aabc435177482cad7cdd556f61a23f
work_keys_str_mv	AT mariagiobergia histopathologiccharacterizationofthereproductiveorgansofheifersexperimentallyinfectedwithcampylobacterfetusvenerealis AT marcelaherrera histopathologiccharacterizationofthereproductiveorgansofheifersexperimentallyinfectedwithcampylobacterfetusvenerealis AT miriamteruel histopathologiccharacterizationofthereproductiveorgansofheifersexperimentallyinfectedwithcampylobacterfetusvenerealis AT belenriccio histopathologiccharacterizationofthereproductiveorgansofheifersexperimentallyinfectedwithcampylobacterfetusvenerealis AT mariacatena histopathologiccharacterizationofthereproductiveorgansofheifersexperimentallyinfectedwithcampylobacterfetusvenerealis
_version_	1718404798128062464

Histopathologic characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis

Ejemplares similares