Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry
Abstract We examined the clinical utility of two multi-locus genetic risk scores (GRSs) previously validated in Europeans among persons of African (AFR; n = 2,089), Latino (LAT; n = 4,349) and East-Asian (EA; n = 4,804) ancestry. We used data from the GERA cohort (30–79 years old, 68 to 73% female)....
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Autores principales: | Carlos Iribarren, Meng Lu, Eric Jorgenson, Manuel Martínez, Carla Lluis-Ganella, Isaac Subirana, Eduardo Salas, Roberto Elosua |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/16ad16b4734e46d19e221465c6c10b06 |
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