AND-1 fork protection function prevents fork resection and is essential for proliferation

AND-1, the vertebrate orthologue of Ctf4, is a critical player during DNA replication and for maintenance of genome integrity. Here the authors use a conditional AND-1 depletion system in avian DT40 cells to reveal the consequences of the lack of AND-1 on cell proliferation and DNA replication.

Guardado en:

Detalles Bibliográficos
Autores principales:	Takuya Abe, Ryotaro Kawasumi, Michele Giannattasio, Sabrina Dusi, Yui Yoshimoto, Keiji Miyata, Koyuki Umemura, Kouji Hirota, Dana Branzei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/16bdca11b36a40e69c41022d7bb4774d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:16bdca11b36a40e69c41022d7bb4774d
record_format	dspace
spelling	oai:doaj.org-article:16bdca11b36a40e69c41022d7bb4774d2021-12-02T15:34:41ZAND-1 fork protection function prevents fork resection and is essential for proliferation10.1038/s41467-018-05586-72041-1723https://doaj.org/article/16bdca11b36a40e69c41022d7bb4774d2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05586-7https://doaj.org/toc/2041-1723AND-1, the vertebrate orthologue of Ctf4, is a critical player during DNA replication and for maintenance of genome integrity. Here the authors use a conditional AND-1 depletion system in avian DT40 cells to reveal the consequences of the lack of AND-1 on cell proliferation and DNA replication.Takuya AbeRyotaro KawasumiMichele GiannattasioSabrina DusiYui YoshimotoKeiji MiyataKoyuki UmemuraKouji HirotaDana BranzeiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Takuya Abe Ryotaro Kawasumi Michele Giannattasio Sabrina Dusi Yui Yoshimoto Keiji Miyata Koyuki Umemura Kouji Hirota Dana Branzei AND-1 fork protection function prevents fork resection and is essential for proliferation
description	AND-1, the vertebrate orthologue of Ctf4, is a critical player during DNA replication and for maintenance of genome integrity. Here the authors use a conditional AND-1 depletion system in avian DT40 cells to reveal the consequences of the lack of AND-1 on cell proliferation and DNA replication.
format	article
author	Takuya Abe Ryotaro Kawasumi Michele Giannattasio Sabrina Dusi Yui Yoshimoto Keiji Miyata Koyuki Umemura Kouji Hirota Dana Branzei
author_facet	Takuya Abe Ryotaro Kawasumi Michele Giannattasio Sabrina Dusi Yui Yoshimoto Keiji Miyata Koyuki Umemura Kouji Hirota Dana Branzei
author_sort	Takuya Abe
title	AND-1 fork protection function prevents fork resection and is essential for proliferation
title_short	AND-1 fork protection function prevents fork resection and is essential for proliferation
title_full	AND-1 fork protection function prevents fork resection and is essential for proliferation
title_fullStr	AND-1 fork protection function prevents fork resection and is essential for proliferation
title_full_unstemmed	AND-1 fork protection function prevents fork resection and is essential for proliferation
title_sort	and-1 fork protection function prevents fork resection and is essential for proliferation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/16bdca11b36a40e69c41022d7bb4774d
work_keys_str_mv	AT takuyaabe and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT ryotarokawasumi and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT michelegiannattasio and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT sabrinadusi and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT yuiyoshimoto and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT keijimiyata and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT koyukiumemura and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT koujihirota and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation AT danabranzei and1forkprotectionfunctionpreventsforkresectionandisessentialforproliferation
_version_	1718386766784757760

AND-1 fork protection function prevents fork resection and is essential for proliferation

Ejemplares similares