Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity

Unnikrishnan Nair,1 Sunil Ganekal,2 Manoj Soman,1 KGR Nair11Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, India; 2Nayana Super Specialty Eye Hospital and Research Center, Davangere, Karnataka, IndiaPurpose: To evaluate the structural changes in the acute phase of central serous...

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Autores principales:	Nair U, Ganekal S, Soman M, Nair KG
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/16c9ca8401a04404aa5721c5b1f5135e
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spelling	oai:doaj.org-article:16c9ca8401a04404aa5721c5b1f5135e2021-12-02T08:32:10ZCorrelation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity1177-54671177-5483https://doaj.org/article/16c9ca8401a04404aa5721c5b1f5135e2012-11-01T00:00:00Zhttp://www.dovepress.com/correlation-of-spectral-domain-optical-coherence-tomography-findings-i-a11607https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Unnikrishnan Nair,1 Sunil Ganekal,2 Manoj Soman,1 KGR Nair11Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, India; 2Nayana Super Specialty Eye Hospital and Research Center, Davangere, Karnataka, IndiaPurpose: To evaluate the structural changes in the acute phase of central serous chorioretinopathy and after its resolution, using spectral domain optical coherence tomography, to correlate these tomographic changes with visual acuity (VA).Method: This was a prospective study of 100 consecutive patients with acute central serous chorioretinopathy. It was based on presenting the best-corrected VA, divided into three groups (Group 1, n = 36, VA 6/6; Group 2, n = 49, VA 6/9&ndash;6/18; Group 3, n = 15, VA &gt; 6/18). All patients underwent fundus evaluation followed by fluorescein angiography and spectral domain optical coherence tomography.Results: The mean age of the patients was 40 &plusmn; 7.17 years. The mean log MAR VA was 0.176 &plusmn; 0.0185. Single pigment epithelial detachment (PED), and multiple discrete and multiple confluent PEDs were seen in 21%, 17%, and 32% of the eyes, respectively. The location of the PED was subfoveal in 35% of the eyes. The presence of subretinal fibrin and a rough undersurface of the neurosensory retina were noted in 61% and 64% of the eyes, respectively. On en-face scanning, a break in the walls of the PED and overlying fibrin were seen in 32.8% and 45% of the eyes, respectively. The mean subretinal fluid height at the fovea was 279.11 &plusmn; 148.78 &micro;. The mean outer nuclear layer thickness during the active stage was 95.10 &micro; and during the resolved stage, it was 77.69 &micro; (P = 0.012). The average photoreceptor lengths were 73.1 &micro;, 84.6 &micro;, and 94.9 &micro; in groups 1, 2, and 3, respectively, in the acute phase; and 69.5 &micro;, 70.8 &micro;, and 61.6 &micro;, respectively, after resolution (P = 0.013, P = 0.010, and P = 0.011).Conclusion: In the acute phase of the disease, poorer VA showed statistically significant association with greater dimensions of subretinal fluid &ndash; particularly, greater subretinal fluid height and thinning of the outer nuclear layer at the fovea. The presence of fibrin, subretinal precipitates, subfoveal location, or type of PED did not have any association with poor VA. In resolved central serous chorioretinopathy, poorer VA was associated with a persistently thinner outer nuclear layer, shorter photoreceptor lengths, and inner and outer segment junction atrophy.Keywords: SD-OCT, acute CSC, ONL thickness, photoreceptor thickness, visual acuity correlationNair UGanekal SSoman MNair KGDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1949-1954 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Nair U Ganekal S Soman M Nair KG Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
description	Unnikrishnan Nair,1 Sunil Ganekal,2 Manoj Soman,1 KGR Nair11Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, India; 2Nayana Super Specialty Eye Hospital and Research Center, Davangere, Karnataka, IndiaPurpose: To evaluate the structural changes in the acute phase of central serous chorioretinopathy and after its resolution, using spectral domain optical coherence tomography, to correlate these tomographic changes with visual acuity (VA).Method: This was a prospective study of 100 consecutive patients with acute central serous chorioretinopathy. It was based on presenting the best-corrected VA, divided into three groups (Group 1, n = 36, VA 6/6; Group 2, n = 49, VA 6/9&ndash;6/18; Group 3, n = 15, VA &gt; 6/18). All patients underwent fundus evaluation followed by fluorescein angiography and spectral domain optical coherence tomography.Results: The mean age of the patients was 40 &plusmn; 7.17 years. The mean log MAR VA was 0.176 &plusmn; 0.0185. Single pigment epithelial detachment (PED), and multiple discrete and multiple confluent PEDs were seen in 21%, 17%, and 32% of the eyes, respectively. The location of the PED was subfoveal in 35% of the eyes. The presence of subretinal fibrin and a rough undersurface of the neurosensory retina were noted in 61% and 64% of the eyes, respectively. On en-face scanning, a break in the walls of the PED and overlying fibrin were seen in 32.8% and 45% of the eyes, respectively. The mean subretinal fluid height at the fovea was 279.11 &plusmn; 148.78 &micro;. The mean outer nuclear layer thickness during the active stage was 95.10 &micro; and during the resolved stage, it was 77.69 &micro; (P = 0.012). The average photoreceptor lengths were 73.1 &micro;, 84.6 &micro;, and 94.9 &micro; in groups 1, 2, and 3, respectively, in the acute phase; and 69.5 &micro;, 70.8 &micro;, and 61.6 &micro;, respectively, after resolution (P = 0.013, P = 0.010, and P = 0.011).Conclusion: In the acute phase of the disease, poorer VA showed statistically significant association with greater dimensions of subretinal fluid &ndash; particularly, greater subretinal fluid height and thinning of the outer nuclear layer at the fovea. The presence of fibrin, subretinal precipitates, subfoveal location, or type of PED did not have any association with poor VA. In resolved central serous chorioretinopathy, poorer VA was associated with a persistently thinner outer nuclear layer, shorter photoreceptor lengths, and inner and outer segment junction atrophy.Keywords: SD-OCT, acute CSC, ONL thickness, photoreceptor thickness, visual acuity correlation
format	article
author	Nair U Ganekal S Soman M Nair KG
author_facet	Nair U Ganekal S Soman M Nair KG
author_sort	Nair U
title	Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
title_short	Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
title_full	Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
title_fullStr	Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
title_full_unstemmed	Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
title_sort	correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/16c9ca8401a04404aa5721c5b1f5135e
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Correlation of spectral domain optical coherence tomography findings in acute central serous chorioretinopathy with visual acuity

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