Bile acids drive the newborn’s gut microbiota maturation

Early postnatal colonization has been described to be critical for the long-term microbiota composition and health. Here, via multi-omics approach, the authors investigate the impact of the developing host hepatic metabolism on the murine intestinal microbiota composition with comparative analysis a...

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Bibliographic Details
Main Authors: N. van Best, U. Rolle-Kampczyk, F. G. Schaap, M. Basic, S. W. M. Olde Damink, A. Bleich, P. H. M. Savelkoul, M. von Bergen, J. Penders, M. W. Hornef
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/16c9facaa9214d2eb9ed43fcaa993850
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Summary:Early postnatal colonization has been described to be critical for the long-term microbiota composition and health. Here, via multi-omics approach, the authors investigate the impact of the developing host hepatic metabolism on the murine intestinal microbiota composition with comparative analysis at immediate postnatal period, early infancy and weaning and adulthood.