Bile acids drive the newborn’s gut microbiota maturation

Early postnatal colonization has been described to be critical for the long-term microbiota composition and health. Here, via multi-omics approach, the authors investigate the impact of the developing host hepatic metabolism on the murine intestinal microbiota composition with comparative analysis a...

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Auteurs principaux: N. van Best, U. Rolle-Kampczyk, F. G. Schaap, M. Basic, S. W. M. Olde Damink, A. Bleich, P. H. M. Savelkoul, M. von Bergen, J. Penders, M. W. Hornef
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/16c9facaa9214d2eb9ed43fcaa993850
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Résumé:Early postnatal colonization has been described to be critical for the long-term microbiota composition and health. Here, via multi-omics approach, the authors investigate the impact of the developing host hepatic metabolism on the murine intestinal microbiota composition with comparative analysis at immediate postnatal period, early infancy and weaning and adulthood.