Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block

Abstract Objective To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). Methods Thirty‐two patients with dilated...

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Autores principales:	Linna Zu, Zefeng Wang, Fei Hang, Yang Jiang, Xinlu Wang, Liting Cheng, Junmeng Zhang, Yongquan Wu
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	cardiac insufficiency cardiac resynchronization therapy left bundle branch area pacing left bundle branch block Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/16ca76bdbe834857918ea5a13fff753a
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spelling	oai:doaj.org-article:16ca76bdbe834857918ea5a13fff753a2021-11-12T11:40:14ZCardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block1542-474X1082-720X10.1111/anec.12898https://doaj.org/article/16ca76bdbe834857918ea5a13fff753a2021-11-01T00:00:00Zhttps://doi.org/10.1111/anec.12898https://doaj.org/toc/1082-720Xhttps://doaj.org/toc/1542-474XAbstract Objective To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). Methods Thirty‐two patients with dilated cardiomyopathy complicated by cardiac insufficiency and left bundle branch block were divided into CRT group and LBBaP group. Parameters including pacing threshold, R‐wave amplitude, pacing impedance and operation time, and X‐ray exposure time were recorded. The left ventricular ejection fraction (LVEF), left ventricular end‐diastolic diameter (LVEDD), and left ventricular end‐systolic diameter (LVESD) were examined by echocardiography. The changes of QRS complex before and after operation were compared. Results Compared with CRT group, the LBBaP group spent less time on total operation time and X‐ray exposure time and had stable electrode parameters including pacing threshold, R‐wave amplitude, and lead impedance after 12‐month follow‐up. In addition, LBBaP can achieve narrow QRS complex (117.15 ± 9.91) ms immediately than that in CRT group (130.32 ± 12.41) ms. The change of QRS between LBBaP is (50.30 ± 23.79) ms and CRT group is (33.15 ± 20.22) ms. After 6 months' follow‐up in LBBaP group, EF was higher than that before operation. Followed up for 12 months after operation, EF and LVEDD in LBBaP group were significantly improved compared with those before operation. Conclusion Left bundle branch area pacing is a safe and effective resynchronization method for patients with cardiac insufficiency and asynchronization, which can achieve same clinical effects to CRT.Linna ZuZefeng WangFei HangYang JiangXinlu WangLiting ChengJunmeng ZhangYongquan WuWileyarticlecardiac insufficiencycardiac resynchronization therapyleft bundle branch area pacingleft bundle branch blockDiseases of the circulatory (Cardiovascular) systemRC666-701ENAnnals of Noninvasive Electrocardiology, Vol 26, Iss 6, Pp n/a-n/a (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiac insufficiency cardiac resynchronization therapy left bundle branch area pacing left bundle branch block Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	cardiac insufficiency cardiac resynchronization therapy left bundle branch area pacing left bundle branch block Diseases of the circulatory (Cardiovascular) system RC666-701 Linna Zu Zefeng Wang Fei Hang Yang Jiang Xinlu Wang Liting Cheng Junmeng Zhang Yongquan Wu Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
description	Abstract Objective To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). Methods Thirty‐two patients with dilated cardiomyopathy complicated by cardiac insufficiency and left bundle branch block were divided into CRT group and LBBaP group. Parameters including pacing threshold, R‐wave amplitude, pacing impedance and operation time, and X‐ray exposure time were recorded. The left ventricular ejection fraction (LVEF), left ventricular end‐diastolic diameter (LVEDD), and left ventricular end‐systolic diameter (LVESD) were examined by echocardiography. The changes of QRS complex before and after operation were compared. Results Compared with CRT group, the LBBaP group spent less time on total operation time and X‐ray exposure time and had stable electrode parameters including pacing threshold, R‐wave amplitude, and lead impedance after 12‐month follow‐up. In addition, LBBaP can achieve narrow QRS complex (117.15 ± 9.91) ms immediately than that in CRT group (130.32 ± 12.41) ms. The change of QRS between LBBaP is (50.30 ± 23.79) ms and CRT group is (33.15 ± 20.22) ms. After 6 months' follow‐up in LBBaP group, EF was higher than that before operation. Followed up for 12 months after operation, EF and LVEDD in LBBaP group were significantly improved compared with those before operation. Conclusion Left bundle branch area pacing is a safe and effective resynchronization method for patients with cardiac insufficiency and asynchronization, which can achieve same clinical effects to CRT.
format	article
author	Linna Zu Zefeng Wang Fei Hang Yang Jiang Xinlu Wang Liting Cheng Junmeng Zhang Yongquan Wu
author_facet	Linna Zu Zefeng Wang Fei Hang Yang Jiang Xinlu Wang Liting Cheng Junmeng Zhang Yongquan Wu
author_sort	Linna Zu
title	Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_short	Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_full	Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_fullStr	Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_full_unstemmed	Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_sort	cardiac resynchronization performed by lbbap‐crt in patients with cardiac insufficiency and left bundle branch block
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/16ca76bdbe834857918ea5a13fff753a
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Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block

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