Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

Despite the importance of G-protein-coupled receptors in many cellular functions, their intracellular organisation is largely unknown. The authors identified periodically repeating clusters of cannabinoid receptor 1 hotspots within neuronal axons that are dynamically regulated by CB1 agonists.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hui Li, Jie Yang, Cuiping Tian, Min Diao, Quan Wang, Simeng Zhao, Shanshan Li, Fangzhi Tan, Tian Hua, Ya Qin, Chao-Po Lin, Dylan Deska-Gauthier, Garth J. Thompson, Ying Zhang, Wenqing Shui, Zhi-Jie Liu, Tong Wang, Guisheng Zhong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/16d642a130464ca1a75800a5fd41828b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:16d642a130464ca1a75800a5fd41828b
record_format	dspace
spelling	oai:doaj.org-article:16d642a130464ca1a75800a5fd41828b2021-12-02T14:40:38ZOrganized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging10.1038/s41467-020-19510-52041-1723https://doaj.org/article/16d642a130464ca1a75800a5fd41828b2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19510-5https://doaj.org/toc/2041-1723Despite the importance of G-protein-coupled receptors in many cellular functions, their intracellular organisation is largely unknown. The authors identified periodically repeating clusters of cannabinoid receptor 1 hotspots within neuronal axons that are dynamically regulated by CB1 agonists.Hui LiJie YangCuiping TianMin DiaoQuan WangSimeng ZhaoShanshan LiFangzhi TanTian HuaYa QinChao-Po LinDylan Deska-GauthierGarth J. ThompsonYing ZhangWenqing ShuiZhi-Jie LiuTong WangGuisheng ZhongNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hui Li Jie Yang Cuiping Tian Min Diao Quan Wang Simeng Zhao Shanshan Li Fangzhi Tan Tian Hua Ya Qin Chao-Po Lin Dylan Deska-Gauthier Garth J. Thompson Ying Zhang Wenqing Shui Zhi-Jie Liu Tong Wang Guisheng Zhong Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
description	Despite the importance of G-protein-coupled receptors in many cellular functions, their intracellular organisation is largely unknown. The authors identified periodically repeating clusters of cannabinoid receptor 1 hotspots within neuronal axons that are dynamically regulated by CB1 agonists.
format	article
author	Hui Li Jie Yang Cuiping Tian Min Diao Quan Wang Simeng Zhao Shanshan Li Fangzhi Tan Tian Hua Ya Qin Chao-Po Lin Dylan Deska-Gauthier Garth J. Thompson Ying Zhang Wenqing Shui Zhi-Jie Liu Tong Wang Guisheng Zhong
author_facet	Hui Li Jie Yang Cuiping Tian Min Diao Quan Wang Simeng Zhao Shanshan Li Fangzhi Tan Tian Hua Ya Qin Chao-Po Lin Dylan Deska-Gauthier Garth J. Thompson Ying Zhang Wenqing Shui Zhi-Jie Liu Tong Wang Guisheng Zhong
author_sort	Hui Li
title	Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
title_short	Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
title_full	Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
title_fullStr	Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
title_full_unstemmed	Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
title_sort	organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/16d642a130464ca1a75800a5fd41828b
work_keys_str_mv	AT huili organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT jieyang organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT cuipingtian organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT mindiao organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT quanwang organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT simengzhao organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT shanshanli organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT fangzhitan organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT tianhua organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT yaqin organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT chaopolin organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT dylandeskagauthier organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT garthjthompson organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT yingzhang organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT wenqingshui organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT zhijieliu organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT tongwang organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging AT guishengzhong organizedcannabinoidreceptordistributioninneuronsrevealedbysuperresolutionfluorescenceimaging
_version_	1718390218694852608

Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

Ejemplares similares