DNA methylation and hydroxymethylation analysis using a high throughput and low bias direct injection mass spectrometry platform

DNA modifications are small covalent chemical groups that modify nucleotides to regulate DNA readout. Anomalous abundance and genome-wide localization of these modifications can negatively tune gene expression and propagate into unbalanced epigenetics regulation, which is known to be associated with...

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Autores principales: Yan Sun, Stephanie Stransky, Jennifer Aguilan, Michael Brenowitz, Simone Sidoli
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/16d6779d59b84a6590e5787db987fe67
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