Output from VIP cells of the mammalian central clock regulates daily physiological rhythms

VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic target neurons and their physiological functions.

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Detalles Bibliográficos
Autores principales: Sarika Paul, Lydia Hanna, Court Harding, Edward A. Hayter, Lauren Walmsley, David A. Bechtold, Timothy M. Brown
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/16d76bcc2be2406ea4926ed3ab5d9eeb
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Sumario:VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic target neurons and their physiological functions.