Output from VIP cells of the mammalian central clock regulates daily physiological rhythms

VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic target neurons and their physiological functions.

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Autores principales: Sarika Paul, Lydia Hanna, Court Harding, Edward A. Hayter, Lauren Walmsley, David A. Bechtold, Timothy M. Brown
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/16d76bcc2be2406ea4926ed3ab5d9eeb
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spelling oai:doaj.org-article:16d76bcc2be2406ea4926ed3ab5d9eeb2021-12-02T14:40:43ZOutput from VIP cells of the mammalian central clock regulates daily physiological rhythms10.1038/s41467-020-15277-x2041-1723https://doaj.org/article/16d76bcc2be2406ea4926ed3ab5d9eeb2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15277-xhttps://doaj.org/toc/2041-1723VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic target neurons and their physiological functions.Sarika PaulLydia HannaCourt HardingEdward A. HayterLauren WalmsleyDavid A. BechtoldTimothy M. BrownNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sarika Paul
Lydia Hanna
Court Harding
Edward A. Hayter
Lauren Walmsley
David A. Bechtold
Timothy M. Brown
Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
description VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic target neurons and their physiological functions.
format article
author Sarika Paul
Lydia Hanna
Court Harding
Edward A. Hayter
Lauren Walmsley
David A. Bechtold
Timothy M. Brown
author_facet Sarika Paul
Lydia Hanna
Court Harding
Edward A. Hayter
Lauren Walmsley
David A. Bechtold
Timothy M. Brown
author_sort Sarika Paul
title Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
title_short Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
title_full Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
title_fullStr Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
title_full_unstemmed Output from VIP cells of the mammalian central clock regulates daily physiological rhythms
title_sort output from vip cells of the mammalian central clock regulates daily physiological rhythms
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/16d76bcc2be2406ea4926ed3ab5d9eeb
work_keys_str_mv AT sarikapaul outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT lydiahanna outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT courtharding outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT edwardahayter outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT laurenwalmsley outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT davidabechtold outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
AT timothymbrown outputfromvipcellsofthemammaliancentralclockregulatesdailyphysiologicalrhythms
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