Data mining: traditional spring festival associated with hypercholesterolemia

Abstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional stud...

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Autores principales:	Danchen Wang, Yutong Zou, Honglei Li, Songlin Yu, Liangyu Xia, Xinqi Cheng, Ling Qiu, Tengda Xu
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Lipid profile Hypercholesterolemia Chinese Dyslipidemia Spring festival Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/16d7af5f54644a8cb2b673d45596ea78
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spelling	oai:doaj.org-article:16d7af5f54644a8cb2b673d45596ea782021-11-07T12:06:30ZData mining: traditional spring festival associated with hypercholesterolemia10.1186/s12872-021-02328-41471-2261https://doaj.org/article/16d7af5f54644a8cb2b673d45596ea782021-11-01T00:00:00Zhttps://doi.org/10.1186/s12872-021-02328-4https://doaj.org/toc/1471-2261Abstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional study based on clinical data from the Laboratory Information System (LIS) and Hospital Information System (HIS) in Peking Union Medical College Hospital from 2014 to 2018. Total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were analyzed. Results The serum TC [male vs. female: (4.71 ± 0.90 vs. 4.56 ± 0.85) mmol/L], TG [male vs. female: (1.71 ± 1.56 vs. 1.02 ± 0.68) mmol/L], and LDL-C [male vs. female: (3.01 ± 0.77 vs. 2.73 ± 0.74) mmol/L] levels were significantly higher in males than in females (P < 0.001); serum HDL-C [male vs. female: (1.18 ± 0.28 vs. 1.50 ± 0.34) mmol/L] was significantly lower in males (P < 0.001). In February, the TC, TG, and LDL-C levels were 8.4%, 16.3%, and 9.3% higher than the lowest levels recorded, respectively. The prevalence of dyslipidemia of the two weeks before the Spring festival was significantly lower than that of the first week after the Spring festival (43.6% (168/385) vs. 54.1% (126/233), P=0.007). Additionally, the prevalence of dyslipidemia was statistically higher in the first week after the Spring Festival than in May–January. Conclusion Higher TC, TG, and LDL-C in winter could be associated with high-fat diets during the Spring Festival. The Spring Festival was immediately followed by a higher lipid concentrations. Thus, we don't recommend lipid assessment or physical examination immediately after the holiday especially Spring festival.Danchen WangYutong ZouHonglei LiSonglin YuLiangyu XiaXinqi ChengLing QiuTengda XuBMCarticleLipid profileHypercholesterolemiaChineseDyslipidemiaSpring festivalDiseases of the circulatory (Cardiovascular) systemRC666-701ENBMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Lipid profile Hypercholesterolemia Chinese Dyslipidemia Spring festival Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Lipid profile Hypercholesterolemia Chinese Dyslipidemia Spring festival Diseases of the circulatory (Cardiovascular) system RC666-701 Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu Data mining: traditional spring festival associated with hypercholesterolemia
description	Abstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional study based on clinical data from the Laboratory Information System (LIS) and Hospital Information System (HIS) in Peking Union Medical College Hospital from 2014 to 2018. Total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were analyzed. Results The serum TC [male vs. female: (4.71 ± 0.90 vs. 4.56 ± 0.85) mmol/L], TG [male vs. female: (1.71 ± 1.56 vs. 1.02 ± 0.68) mmol/L], and LDL-C [male vs. female: (3.01 ± 0.77 vs. 2.73 ± 0.74) mmol/L] levels were significantly higher in males than in females (P < 0.001); serum HDL-C [male vs. female: (1.18 ± 0.28 vs. 1.50 ± 0.34) mmol/L] was significantly lower in males (P < 0.001). In February, the TC, TG, and LDL-C levels were 8.4%, 16.3%, and 9.3% higher than the lowest levels recorded, respectively. The prevalence of dyslipidemia of the two weeks before the Spring festival was significantly lower than that of the first week after the Spring festival (43.6% (168/385) vs. 54.1% (126/233), P=0.007). Additionally, the prevalence of dyslipidemia was statistically higher in the first week after the Spring Festival than in May–January. Conclusion Higher TC, TG, and LDL-C in winter could be associated with high-fat diets during the Spring Festival. The Spring Festival was immediately followed by a higher lipid concentrations. Thus, we don't recommend lipid assessment or physical examination immediately after the holiday especially Spring festival.
format	article
author	Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu
author_facet	Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu
author_sort	Danchen Wang
title	Data mining: traditional spring festival associated with hypercholesterolemia
title_short	Data mining: traditional spring festival associated with hypercholesterolemia
title_full	Data mining: traditional spring festival associated with hypercholesterolemia
title_fullStr	Data mining: traditional spring festival associated with hypercholesterolemia
title_full_unstemmed	Data mining: traditional spring festival associated with hypercholesterolemia
title_sort	data mining: traditional spring festival associated with hypercholesterolemia
publisher	BMC
publishDate	2021
url	https://doaj.org/article/16d7af5f54644a8cb2b673d45596ea78
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Data mining: traditional spring festival associated with hypercholesterolemia

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