3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering

In this study, three-dimensional tissue scaffolds were fabricated using a 3D printing process. Chitosan (CS) was used as a matrix polymer, and Osage orange extract (OGE) with different amounts was added as a bioactive material. The scaffolds were characterized by SEM, FTIR, tensile testing, antibact...

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Autores principales:	Elif Saatcioglu, Muge Koyun, Songul Ulag, Ali Sahin, Betul Karademir Yilmaz, Burak Aksu, Oguzhan Gunduz
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Chitosan Maclura pomifera Osage orange Wound healing 3D printing Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/16e48f5322074453b10c3844b55fd12a
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id	oai:doaj.org-article:16e48f5322074453b10c3844b55fd12a
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spelling	oai:doaj.org-article:16e48f5322074453b10c3844b55fd12a2021-11-28T04:39:43Z3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering2667-025910.1016/j.fhfh.2021.100039https://doaj.org/article/16e48f5322074453b10c3844b55fd12a2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667025921000315https://doaj.org/toc/2667-0259In this study, three-dimensional tissue scaffolds were fabricated using a 3D printing process. Chitosan (CS) was used as a matrix polymer, and Osage orange extract (OGE) with different amounts was added as a bioactive material. The scaffolds were characterized by SEM, FTIR, tensile testing, antibacterial, and biocompatibility tests. The SEM images revealed that scaffolds had homogeneous morphology, and the size of the pores ranged from 160 µm to 270 µm. FTIR spectrum of the extracted Osage Orange confirmed the successful extraction of the Osage Orange. The OGE addition decreased the swelling capacity of the CS scaffold proportionally. Biocompatibility results proved the biostability properties of the scaffolds. According to the results, the antibacterial activity of the scaffolds against the Staphylococcus Aureus (S. aureus) and Enterococcus Faecalis (E. faecalis) should be provided after detailed optimization.Elif SaatciogluMuge KoyunSongul UlagAli SahinBetul Karademir YilmazBurak AksuOguzhan GunduzElsevierarticleChitosanMaclura pomiferaOsage orangeWound healing3D printingNutrition. Foods and food supplyTX341-641Nutritional diseases. Deficiency diseasesRC620-627ENFood Hydrocolloids for Health, Vol 1, Iss , Pp 100039- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chitosan Maclura pomifera Osage orange Wound healing 3D printing Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	Chitosan Maclura pomifera Osage orange Wound healing 3D printing Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627 Elif Saatcioglu Muge Koyun Songul Ulag Ali Sahin Betul Karademir Yilmaz Burak Aksu Oguzhan Gunduz 3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
description	In this study, three-dimensional tissue scaffolds were fabricated using a 3D printing process. Chitosan (CS) was used as a matrix polymer, and Osage orange extract (OGE) with different amounts was added as a bioactive material. The scaffolds were characterized by SEM, FTIR, tensile testing, antibacterial, and biocompatibility tests. The SEM images revealed that scaffolds had homogeneous morphology, and the size of the pores ranged from 160 µm to 270 µm. FTIR spectrum of the extracted Osage Orange confirmed the successful extraction of the Osage Orange. The OGE addition decreased the swelling capacity of the CS scaffold proportionally. Biocompatibility results proved the biostability properties of the scaffolds. According to the results, the antibacterial activity of the scaffolds against the Staphylococcus Aureus (S. aureus) and Enterococcus Faecalis (E. faecalis) should be provided after detailed optimization.
format	article
author	Elif Saatcioglu Muge Koyun Songul Ulag Ali Sahin Betul Karademir Yilmaz Burak Aksu Oguzhan Gunduz
author_facet	Elif Saatcioglu Muge Koyun Songul Ulag Ali Sahin Betul Karademir Yilmaz Burak Aksu Oguzhan Gunduz
author_sort	Elif Saatcioglu
title	3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
title_short	3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
title_full	3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
title_fullStr	3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
title_full_unstemmed	3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering
title_sort	3d printing of osage orange extract/chitosan scaffolds for soft tissue engineering
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/16e48f5322074453b10c3844b55fd12a
work_keys_str_mv	AT elifsaatcioglu 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT mugekoyun 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT songululag 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT alisahin 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT betulkarademiryilmaz 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT burakaksu 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering AT oguzhangunduz 3dprintingofosageorangeextractchitosanscaffoldsforsofttissueengineering
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3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering

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