Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application

Abstract Numerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/...

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Autores principales:	Sopit Phetsang, Pinit Kidkhunthod, Narong Chanlek, Jaroon Jakmunee, Pitchaya Mungkornasawakul, Kontad Ounnunkad
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/16e5b3ccc0d34006ad69254e5562fbc9
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spelling	oai:doaj.org-article:16e5b3ccc0d34006ad69254e5562fbc92021-12-02T13:41:10ZCopper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application10.1038/s41598-021-88747-x2045-2322https://doaj.org/article/16e5b3ccc0d34006ad69254e5562fbc92021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88747-xhttps://doaj.org/toc/2045-2322Abstract Numerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/reduced graphene oxide modified screen-printed carbon electrode is demonstrated. Facile fabrication of the developed sensing electrodes is carried out by the adsorption of copper(II) onto graphene oxide modified electrode, then following the electrochemical reduction. The proposed sensor illustrates good electrocatalytic activity toward glucose oxidation with a wide linear detection range from 0.10 mM to 12.5 mM, low detection limit of 65 µM, and high sensitivity of 172 μA mM–1 cm–2 along with satisfactory anti-interference ability, reproducibility, stability, and the acceptable recoveries for the detection of glucose in a human serum sample (95.6–106.4%). The copper(II)/reduced graphene oxide based sensor with the superior performances is a great potential for the quantitation of glucose in real samples.Sopit PhetsangPinit KidkhunthodNarong ChanlekJaroon JakmuneePitchaya MungkornasawakulKontad OunnunkadNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sopit Phetsang Pinit Kidkhunthod Narong Chanlek Jaroon Jakmunee Pitchaya Mungkornasawakul Kontad Ounnunkad Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
description	Abstract Numerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/reduced graphene oxide modified screen-printed carbon electrode is demonstrated. Facile fabrication of the developed sensing electrodes is carried out by the adsorption of copper(II) onto graphene oxide modified electrode, then following the electrochemical reduction. The proposed sensor illustrates good electrocatalytic activity toward glucose oxidation with a wide linear detection range from 0.10 mM to 12.5 mM, low detection limit of 65 µM, and high sensitivity of 172 μA mM–1 cm–2 along with satisfactory anti-interference ability, reproducibility, stability, and the acceptable recoveries for the detection of glucose in a human serum sample (95.6–106.4%). The copper(II)/reduced graphene oxide based sensor with the superior performances is a great potential for the quantitation of glucose in real samples.
format	article
author	Sopit Phetsang Pinit Kidkhunthod Narong Chanlek Jaroon Jakmunee Pitchaya Mungkornasawakul Kontad Ounnunkad
author_facet	Sopit Phetsang Pinit Kidkhunthod Narong Chanlek Jaroon Jakmunee Pitchaya Mungkornasawakul Kontad Ounnunkad
author_sort	Sopit Phetsang
title	Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
title_short	Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
title_full	Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
title_fullStr	Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
title_full_unstemmed	Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
title_sort	copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/16e5b3ccc0d34006ad69254e5562fbc9
work_keys_str_mv	AT sopitphetsang copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication AT pinitkidkhunthod copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication AT narongchanlek copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication AT jaroonjakmunee copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication AT pitchayamungkornasawakul copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication AT kontadounnunkad copperreducedgrapheneoxidefilmmodifiedelectrodefornonenzymaticglucosesensingapplication
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Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application

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