Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study

Ke-Vin Chang,1,2 Kuen-Cheh Yang,3–5 Wei-Ting Wu,1,2 Kuo-Chin Huang,3–5 Der-Sheng Han1,2,5 1Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan; 2Department of Physical Medicine and Rehabilitation, National Taiwan...

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Autores principales:	Chang KV, Yang KC, Wu WT, Huang KC, Han DS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Metabolic syndrome sarcopenia sonography nutrition obesity Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/16ea699f1ef2467bb28b0f207b4b6369
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spelling	oai:doaj.org-article:16ea699f1ef2467bb28b0f207b4b63692021-12-02T03:08:07ZAssociation between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study1178-7007https://doaj.org/article/16ea699f1ef2467bb28b0f207b4b63692019-09-01T00:00:00Zhttps://www.dovepress.com/association-between-metabolic-syndrome-and-limb-muscle-quantity-and-qu-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Ke-Vin Chang,1,2 Kuen-Cheh Yang,3–5 Wei-Ting Wu,1,2 Kuo-Chin Huang,3–5 Der-Sheng Han1,2,5 1Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan; 2Department of Physical Medicine and Rehabilitation, National Taiwan University College of Medicine, Taipei, Taiwan; 3Department of Family Medicine, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan; 4Department of Family Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; 5Health Science and Wellness Center, National Taiwan University, Taipei, TaiwanCorrespondence: Der-Sheng HanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, BeiHu Branch, No. 87, Nei-Jiang Road, Wan-Hwa District, Taipei 108, TaiwanTel +886 223 717 101 5001Email dshan1121@yahoo.com.twPurpose: Limited imaging studies have investigated whether limb muscle quantity and quality change after metabolic syndrome (MetS) development. This pilot study examined MetS influence on limb muscle characteristics in older adults.Methods: Participants were recruited from annual health examinations; their right biceps brachii, triceps brachii, rectus femoris, and gastrocnemius muscles were measured by ultrasound. Anthropometric parameters, blood biochemistry, and physical performance (handgrip strength and gait speed) were also examined.Results: Overall, 129 participants were enrolled, including 26 with MetS. Although handgrip strength was lower in MetS patients, there were no significant between-group differences considering thickness and mean echogenicity of the four muscles. Handgrip strength was positively correlated with the thickness of biceps brachii, triceps brachii, and rectus femoris but was negatively associated with their echogenicity. On multivariate analysis, triceps muscle echogenicity was trivially associated (odds ratio, 0.93; 95% confidence interval, 0.86–0.99) with MetS, possibly due to multicollinearity with grip strength.Conclusion: No significant difference was recognized in limb muscle thickness and echogenicity in the geriatric population with MetS compared with healthy controls by ultrasound imaging. However, the finding might be caused by the small sample size of our participants. Future large-scale studies should explore the influence of separated risk factors of MetS on limb muscle echotexture and examine whether manifestation differs in different age populations.Keywords: metabolic syndrome, sarcopenia, sonography, nutrition, obesityChang KVYang KCWu WTHuang KCHan DSDove Medical PressarticleMetabolic syndromesarcopeniasonographynutritionobesitySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 1821-1830 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Metabolic syndrome sarcopenia sonography nutrition obesity Specialties of internal medicine RC581-951
spellingShingle	Metabolic syndrome sarcopenia sonography nutrition obesity Specialties of internal medicine RC581-951 Chang KV Yang KC Wu WT Huang KC Han DS Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
description	Ke-Vin Chang,1,2 Kuen-Cheh Yang,3–5 Wei-Ting Wu,1,2 Kuo-Chin Huang,3–5 Der-Sheng Han1,2,5 1Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan; 2Department of Physical Medicine and Rehabilitation, National Taiwan University College of Medicine, Taipei, Taiwan; 3Department of Family Medicine, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan; 4Department of Family Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; 5Health Science and Wellness Center, National Taiwan University, Taipei, TaiwanCorrespondence: Der-Sheng HanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, BeiHu Branch, No. 87, Nei-Jiang Road, Wan-Hwa District, Taipei 108, TaiwanTel +886 223 717 101 5001Email dshan1121@yahoo.com.twPurpose: Limited imaging studies have investigated whether limb muscle quantity and quality change after metabolic syndrome (MetS) development. This pilot study examined MetS influence on limb muscle characteristics in older adults.Methods: Participants were recruited from annual health examinations; their right biceps brachii, triceps brachii, rectus femoris, and gastrocnemius muscles were measured by ultrasound. Anthropometric parameters, blood biochemistry, and physical performance (handgrip strength and gait speed) were also examined.Results: Overall, 129 participants were enrolled, including 26 with MetS. Although handgrip strength was lower in MetS patients, there were no significant between-group differences considering thickness and mean echogenicity of the four muscles. Handgrip strength was positively correlated with the thickness of biceps brachii, triceps brachii, and rectus femoris but was negatively associated with their echogenicity. On multivariate analysis, triceps muscle echogenicity was trivially associated (odds ratio, 0.93; 95% confidence interval, 0.86–0.99) with MetS, possibly due to multicollinearity with grip strength.Conclusion: No significant difference was recognized in limb muscle thickness and echogenicity in the geriatric population with MetS compared with healthy controls by ultrasound imaging. However, the finding might be caused by the small sample size of our participants. Future large-scale studies should explore the influence of separated risk factors of MetS on limb muscle echotexture and examine whether manifestation differs in different age populations.Keywords: metabolic syndrome, sarcopenia, sonography, nutrition, obesity
format	article
author	Chang KV Yang KC Wu WT Huang KC Han DS
author_facet	Chang KV Yang KC Wu WT Huang KC Han DS
author_sort	Chang KV
title	Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
title_short	Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
title_full	Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
title_fullStr	Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
title_full_unstemmed	Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
title_sort	association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/16ea699f1ef2467bb28b0f207b4b6369
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_version_	1718401902992949248

Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study

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