Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients

There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This commentary highlights an extraordinary international collabor...

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Autores principales:	S. G. P. Funnell, W. E. Dowling, C. Muñoz-Fontela, P.-S. Gsell, D. E. Ingber, G. A. Hamilton, L. Delang, J. Rocha-Pereira, S. Kaptein, K. H. Dallmeier, J. Neyts, K. Rosenke, E. de Wit, H. Feldmann, P. Maisonnasse, R. Le Grand, M. B. Frieman, C. M. Coleman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/16f0fbaa1ef74b81ae8f7a0d0a46c7fa
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spelling	oai:doaj.org-article:16f0fbaa1ef74b81ae8f7a0d0a46c7fa2021-12-02T15:09:26ZEmerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients10.1038/s41467-020-17907-w2041-1723https://doaj.org/article/16f0fbaa1ef74b81ae8f7a0d0a46c7fa2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17907-whttps://doaj.org/toc/2041-1723There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This commentary highlights an extraordinary international collaborative effort of independent researchers who have recently all come to the same conclusion—that chloroquine or hydroxchloroquine are unlikely to provide clinical benefit against COVID-19.S. G. P. FunnellW. E. DowlingC. Muñoz-FontelaP.-S. GsellD. E. IngberG. A. HamiltonL. DelangJ. Rocha-PereiraS. KapteinK. H. DallmeierJ. NeytsK. RosenkeE. de WitH. FeldmannP. MaisonnasseR. Le GrandM. B. FriemanC. M. ColemanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q S. G. P. Funnell W. E. Dowling C. Muñoz-Fontela P.-S. Gsell D. E. Ingber G. A. Hamilton L. Delang J. Rocha-Pereira S. Kaptein K. H. Dallmeier J. Neyts K. Rosenke E. de Wit H. Feldmann P. Maisonnasse R. Le Grand M. B. Frieman C. M. Coleman Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
description	There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This commentary highlights an extraordinary international collaborative effort of independent researchers who have recently all come to the same conclusion—that chloroquine or hydroxchloroquine are unlikely to provide clinical benefit against COVID-19.
format	article
author	S. G. P. Funnell W. E. Dowling C. Muñoz-Fontela P.-S. Gsell D. E. Ingber G. A. Hamilton L. Delang J. Rocha-Pereira S. Kaptein K. H. Dallmeier J. Neyts K. Rosenke E. de Wit H. Feldmann P. Maisonnasse R. Le Grand M. B. Frieman C. M. Coleman
author_facet	S. G. P. Funnell W. E. Dowling C. Muñoz-Fontela P.-S. Gsell D. E. Ingber G. A. Hamilton L. Delang J. Rocha-Pereira S. Kaptein K. H. Dallmeier J. Neyts K. Rosenke E. de Wit H. Feldmann P. Maisonnasse R. Le Grand M. B. Frieman C. M. Coleman
author_sort	S. G. P. Funnell
title	Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
title_short	Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
title_full	Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
title_fullStr	Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
title_full_unstemmed	Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
title_sort	emerging preclinical evidence does not support broad use of hydroxychloroquine in covid-19 patients
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/16f0fbaa1ef74b81ae8f7a0d0a46c7fa
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Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients

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