Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma

Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma

Pancreatic stellate cells (PSCs) mainly consist of cancer-associating fibroblasts in pancreatic ductal adenocarcinoma (PDAC). The receptor for advanced glycation end products (RAGE) is implicated in the pathophysiology of diabetic complications. Here, we studied the implication of RAGE in PSC activa...

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Main Authors: Chiaki Uchida, Hiroki Mizukami, Yutaro Hara, Takeshi Saito, Satoko Umetsu, Akiko Igawa, Sho Osonoi, Kazuhiro Kudoh, Yasuhiko Yamamoto, Hiroshi Yamamoto, Soroku Yagihashi, Kenichi Hakamada
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
type 2 diabetes
advanced glycation end products
pancreatic ductal adenocarcinoma
RAGE
EMT
metabolic syndrome
Biology (General)
QH301-705.5
Chemistry
QD1-999
Online Access:https://doaj.org/article/17044c4b692544f5832864a0407f0f4f
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https://doaj.org/article/17044c4b692544f5832864a0407f0f4f

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