Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection

Aim: to analyze the effectiveness of intravenous ozone therapy in long COVID-19 patients experienced community-acquired polysegmental pneumonia (associated with SARS-CoV2 infection). Materials and methods. The study involved 42 long COVID-19 individuals aged 41–82 years who underwent rehabilitati...

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Autores principales:	I. B. Baranova, A. F. Gumeniuk, A. I. Semenenko, I. A. Iliuk, I. P. Osypenko
Formato:	article
Lenguaje:	EN RU UK
Publicado:	Zaporozhye State Medical University 2021
Materias:	rehabilitation ozonotherapy pneumonia viral sars-cov2 infection long-term covid-19 Medicine R
Acceso en línea:	https://doi.org/10.14739/2310-1210.2021.6.233891 https://doaj.org/article/17137e2bcd9242af96e785f7628b162e
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spelling	oai:doaj.org-article:17137e2bcd9242af96e785f7628b162e2021-11-04T09:24:27ZOzone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infectionhttps://doi.org/10.14739/2310-1210.2021.6.2338912306-41452310-1210https://doaj.org/article/17137e2bcd9242af96e785f7628b162e2021-11-01T00:00:00Zhttp://zmj.zsmu.edu.ua/article/view/233891/241651https://doaj.org/toc/2306-4145https://doaj.org/toc/2310-1210Aim: to analyze the effectiveness of intravenous ozone therapy in long COVID-19 patients experienced community-acquired polysegmental pneumonia (associated with SARS-CoV2 infection). Materials and methods. The study involved 42 long COVID-19 individuals aged 41–82 years who underwent rehabilitation after community-acquired polysegmental pneumonia associated with SARS-CoV2 infection. The patients were examined and followed up subjectively (by the G. Borg and PCFS scales) and objectively (oxygen saturation, C-reactive protein, ferritin, D-dimer, urea and creatinine, 6-minute walk test). All patients received similar medicamentous therapy, and combined intravenous ozone therapy was additionally prescribed to the main group patients (n = 21): an alternate-day infusion of 200 ml ozonized saline at a concentration of 20 mg/ml and major autohemotherapy (100 ml ozonized saline at a concentration of 30 mg/ml mixed with 100 ml of the patient’s blood), 10 sessions per treatment course. Results. The integrated approach to the complex program of long COVID-19 treatment and rehabilitation for patients after pneumonia associated with SARS-CoV2 infection using intravenous ozone therapy has demonstrated its significant effectiveness based on the objective and subjective findings (P < 0.01). Twice as many patients in the main group (n = 18) achieved endpoints of the study (absence of dyspnea, normalization of blood biochemical markers and oxygen saturation levels, restoration of exercise tolerance) as compared to the control group (n = 9). Conclusions. The use of combined intravenous ozone therapy (alternating infusion of ozonized saline and ozonized saline mixed with the patient’s blood) in the rehabilitation program for patients after experienced community-acquired polysegmental pneumonia associated with SARS-CoV2 infection is pathogenetically substantiated, effective and cost-effective addition to complex health recovery tools. I. B. BaranovaA. F. GumeniukA. I. SemenenkoI. A. IliukI. P. OsypenkoZaporozhye State Medical Universityarticlerehabilitationozonotherapypneumonia viralsars-cov2 infectionlong-term covid-19MedicineRENRUUKZaporožskij Medicinskij Žurnal, Vol 23, Iss 6, Pp 752-758 (2021)
institution	DOAJ
collection	DOAJ
language	EN RU UK
topic	rehabilitation ozonotherapy pneumonia viral sars-cov2 infection long-term covid-19 Medicine R
spellingShingle	rehabilitation ozonotherapy pneumonia viral sars-cov2 infection long-term covid-19 Medicine R I. B. Baranova A. F. Gumeniuk A. I. Semenenko I. A. Iliuk I. P. Osypenko Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
description	Aim: to analyze the effectiveness of intravenous ozone therapy in long COVID-19 patients experienced community-acquired polysegmental pneumonia (associated with SARS-CoV2 infection). Materials and methods. The study involved 42 long COVID-19 individuals aged 41–82 years who underwent rehabilitation after community-acquired polysegmental pneumonia associated with SARS-CoV2 infection. The patients were examined and followed up subjectively (by the G. Borg and PCFS scales) and objectively (oxygen saturation, C-reactive protein, ferritin, D-dimer, urea and creatinine, 6-minute walk test). All patients received similar medicamentous therapy, and combined intravenous ozone therapy was additionally prescribed to the main group patients (n = 21): an alternate-day infusion of 200 ml ozonized saline at a concentration of 20 mg/ml and major autohemotherapy (100 ml ozonized saline at a concentration of 30 mg/ml mixed with 100 ml of the patient’s blood), 10 sessions per treatment course. Results. The integrated approach to the complex program of long COVID-19 treatment and rehabilitation for patients after pneumonia associated with SARS-CoV2 infection using intravenous ozone therapy has demonstrated its significant effectiveness based on the objective and subjective findings (P < 0.01). Twice as many patients in the main group (n = 18) achieved endpoints of the study (absence of dyspnea, normalization of blood biochemical markers and oxygen saturation levels, restoration of exercise tolerance) as compared to the control group (n = 9). Conclusions. The use of combined intravenous ozone therapy (alternating infusion of ozonized saline and ozonized saline mixed with the patient’s blood) in the rehabilitation program for patients after experienced community-acquired polysegmental pneumonia associated with SARS-CoV2 infection is pathogenetically substantiated, effective and cost-effective addition to complex health recovery tools.
format	article
author	I. B. Baranova A. F. Gumeniuk A. I. Semenenko I. A. Iliuk I. P. Osypenko
author_facet	I. B. Baranova A. F. Gumeniuk A. I. Semenenko I. A. Iliuk I. P. Osypenko
author_sort	I. B. Baranova
title	Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
title_short	Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
title_full	Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
title_fullStr	Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
title_full_unstemmed	Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection
title_sort	ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with sars-cov2 infection
publisher	Zaporozhye State Medical University
publishDate	2021
url	https://doi.org/10.14739/2310-1210.2021.6.233891 https://doaj.org/article/17137e2bcd9242af96e785f7628b162e
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Ozone therapy as a component of a comprehensive rehabilitation program for patients after polysegmental pneumonia associated with SARS-CoV2 infection

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