Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model.

Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model.

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in many critical cellular processes, including proliferation, migration, and angiogenesis, through interaction with a family of five G protein-coupled receptors (S1P1-5). Some reports have implicated S1P as an important in...

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Autores principales: Ken Murakami, Masataka Kohno, Masatoshi Kadoya, Hidetake Nagahara, Wataru Fujii, Takahiro Seno, Aihiro Yamamoto, Ryo Oda, Hiroyoshi Fujiwara, Toshikazu Kubo, Satoshi Morita, Hiroshi Nakada, Timothy Hla, Yutaka Kawahito
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/172555b6a02d4e149684be58e8f01622
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