Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model.

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in many critical cellular processes, including proliferation, migration, and angiogenesis, through interaction with a family of five G protein-coupled receptors (S1P1-5). Some reports have implicated S1P as an important in...

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Autores principales:	Ken Murakami, Masataka Kohno, Masatoshi Kadoya, Hidetake Nagahara, Wataru Fujii, Takahiro Seno, Aihiro Yamamoto, Ryo Oda, Hiroyoshi Fujiwara, Toshikazu Kubo, Satoshi Morita, Hiroshi Nakada, Timothy Hla, Yutaka Kawahito
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/172555b6a02d4e149684be58e8f01622
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Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model.

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