The past and future of tuberculosis research.

Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of...

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Autores principales:	Iñaki Comas, Sebastien Gagneux
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/173cb504a4ae4c15a6e319cffaf676fc
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spelling	oai:doaj.org-article:173cb504a4ae4c15a6e319cffaf676fc2021-11-25T05:48:33ZThe past and future of tuberculosis research.1553-73661553-737410.1371/journal.ppat.1000600https://doaj.org/article/173cb504a4ae4c15a6e319cffaf676fc2009-10-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19855821/?tool=EBIhttps://doaj.org/toc/1553-7366https://doaj.org/toc/1553-7374Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of the disease will remain a formidable challenge for years to come. New high-throughput genomics technologies are already contributing to studies of TB's epidemiology, comparative genomics, evolution, and host-pathogen interaction. We argue here, however, that new multidisciplinary approaches--especially the integration of epidemiology with systems biology in what we call "systems epidemiology"--will be required to eliminate TB.Iñaki ComasSebastien GagneuxPublic Library of Science (PLoS)articleImmunologic diseases. AllergyRC581-607Biology (General)QH301-705.5ENPLoS Pathogens, Vol 5, Iss 10, p e1000600 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
spellingShingle	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5 Iñaki Comas Sebastien Gagneux The past and future of tuberculosis research.
description	Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of the disease will remain a formidable challenge for years to come. New high-throughput genomics technologies are already contributing to studies of TB's epidemiology, comparative genomics, evolution, and host-pathogen interaction. We argue here, however, that new multidisciplinary approaches--especially the integration of epidemiology with systems biology in what we call "systems epidemiology"--will be required to eliminate TB.
format	article
author	Iñaki Comas Sebastien Gagneux
author_facet	Iñaki Comas Sebastien Gagneux
author_sort	Iñaki Comas
title	The past and future of tuberculosis research.
title_short	The past and future of tuberculosis research.
title_full	The past and future of tuberculosis research.
title_fullStr	The past and future of tuberculosis research.
title_full_unstemmed	The past and future of tuberculosis research.
title_sort	past and future of tuberculosis research.
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/173cb504a4ae4c15a6e319cffaf676fc
work_keys_str_mv	AT inakicomas thepastandfutureoftuberculosisresearch AT sebastiengagneux thepastandfutureoftuberculosisresearch AT inakicomas pastandfutureoftuberculosisresearch AT sebastiengagneux pastandfutureoftuberculosisresearch
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The past and future of tuberculosis research.

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