FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1

FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1

Peter's Anomaly is a developmental disorder of the eye and has been linked to mutations in a range of genes, including the transcription factor FOXE3. Here the authors use next-generation RNA sequencing and mass spectrometry to identify an autophagy-associated protein, DNAJB1 as the transcripti...

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Autores principales: Shahid Y. Khan, Shivakumar Vasanth, Firoz Kabir, John D. Gottsch, Arif O. Khan, Raghothama Chaerkady, Mei-Chong W. Lee, Carmen C. Leitch, Zhiwei Ma, Julie Laux, Rafael Villasmil, Shaheen N. Khan, Sheikh Riazuddin, Javed Akram, Robert N. Cole, C. Conover Talbot, Nader Pourmand, Norann A. Zaghloul, J. Fielding Hejtmancik, S. Amer Riazuddin
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1749f175df8b441e834b71a3a43eae2b
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spelling oai:doaj.org-article:1749f175df8b441e834b71a3a43eae2b2021-12-02T17:31:18ZFOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB110.1038/ncomms109532041-1723https://doaj.org/article/1749f175df8b441e834b71a3a43eae2b2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms10953https://doaj.org/toc/2041-1723Peter's Anomaly is a developmental disorder of the eye and has been linked to mutations in a range of genes, including the transcription factor FOXE3. Here the authors use next-generation RNA sequencing and mass spectrometry to identify an autophagy-associated protein, DNAJB1 as the transcriptional target of FOXE3.Shahid Y. KhanShivakumar VasanthFiroz KabirJohn D. GottschArif O. KhanRaghothama ChaerkadyMei-Chong W. LeeCarmen C. LeitchZhiwei MaJulie LauxRafael VillasmilShaheen N. KhanSheikh RiazuddinJaved AkramRobert N. ColeC. Conover TalbotNader PourmandNorann A. ZaghloulJ. Fielding HejtmancikS. Amer RiazuddinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shahid Y. Khan
Shivakumar Vasanth
Firoz Kabir
John D. Gottsch
Arif O. Khan
Raghothama Chaerkady
Mei-Chong W. Lee
Carmen C. Leitch
Zhiwei Ma
Julie Laux
Rafael Villasmil
Shaheen N. Khan
Sheikh Riazuddin
Javed Akram
Robert N. Cole
C. Conover Talbot
Nader Pourmand
Norann A. Zaghloul
J. Fielding Hejtmancik
S. Amer Riazuddin
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
description Peter's Anomaly is a developmental disorder of the eye and has been linked to mutations in a range of genes, including the transcription factor FOXE3. Here the authors use next-generation RNA sequencing and mass spectrometry to identify an autophagy-associated protein, DNAJB1 as the transcriptional target of FOXE3.
format article
author Shahid Y. Khan
Shivakumar Vasanth
Firoz Kabir
John D. Gottsch
Arif O. Khan
Raghothama Chaerkady
Mei-Chong W. Lee
Carmen C. Leitch
Zhiwei Ma
Julie Laux
Rafael Villasmil
Shaheen N. Khan
Sheikh Riazuddin
Javed Akram
Robert N. Cole
C. Conover Talbot
Nader Pourmand
Norann A. Zaghloul
J. Fielding Hejtmancik
S. Amer Riazuddin
author_facet Shahid Y. Khan
Shivakumar Vasanth
Firoz Kabir
John D. Gottsch
Arif O. Khan
Raghothama Chaerkady
Mei-Chong W. Lee
Carmen C. Leitch
Zhiwei Ma
Julie Laux
Rafael Villasmil
Shaheen N. Khan
Sheikh Riazuddin
Javed Akram
Robert N. Cole
C. Conover Talbot
Nader Pourmand
Norann A. Zaghloul
J. Fielding Hejtmancik
S. Amer Riazuddin
author_sort Shahid Y. Khan
title FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
title_short FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
title_full FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
title_fullStr FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
title_full_unstemmed FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
title_sort foxe3 contributes to peters anomaly through transcriptional regulation of an autophagy-associated protein termed dnajb1
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1749f175df8b441e834b71a3a43eae2b
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