Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice

Cancer stem cells (CSC) have been shown as the origin for therapeutic resistance and patient relapse. Here, the authors show that targeting Arf1-mediated lipid metabolism in CSC induces cell death but also an immunogenic anti-cancer response.

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Autores principales: Guohao Wang, Junji Xu, Jiangsha Zhao, Weiqin Yin, Dayong Liu, WanJun Chen, Steven X. Hou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/174cbfcf447b4a919eb206138ce1043c
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