Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies

Drug formulation: Easing the toll of caregiving Switching from oral to long-acting injectable antipsychotic medication improves overall caregiver burden. The physical, emotional and financial toll of providing care for patients with schizophrenia is often underestimated. Poor adherence to convention...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Srihari Gopal, Haiyan Xu, Kelly McQuarrie, Adam Savitz, Isaac Nuamah, Kimberly Woodruff, Maju Mathews
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Psychiatry RC435-571
Acceso en línea:	https://doaj.org/article/174df3333f1542aba31699e1d40b0a99
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:174df3333f1542aba31699e1d40b0a99
record_format	dspace
spelling	oai:doaj.org-article:174df3333f1542aba31699e1d40b0a992021-12-02T15:18:49ZCaregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies10.1038/s41537-017-0025-52334-265Xhttps://doaj.org/article/174df3333f1542aba31699e1d40b0a992017-07-01T00:00:00Zhttps://doi.org/10.1038/s41537-017-0025-5https://doaj.org/toc/2334-265XDrug formulation: Easing the toll of caregiving Switching from oral to long-acting injectable antipsychotic medication improves overall caregiver burden. The physical, emotional and financial toll of providing care for patients with schizophrenia is often underestimated. Poor adherence to conventional oral antipsychotics is a major cause of symptomatic relapse in patients and of stress for carers. Srihari Gopal and colleagues at Janssen Pharmaceuticals have pooled data from two large studies involving 1498 caregivers across 27 countries. They found that administration of either 1- or 3-monthly long-acting injectable antipsychotics not only eased the burden of daily dosing and patient compliance, but also had a positive impact on the stress conditions of caregivers. Using the Involvement Evaluation Questionnaire to measure caregiver burden, the authors showed that the switch in drug formulation decreased the need to urge patients to self-care and the hours spent caregiving.Srihari GopalHaiyan XuKelly McQuarrieAdam SavitzIsaac NuamahKimberly WoodruffMaju MathewsNature PortfolioarticlePsychiatryRC435-571ENnpj Schizophrenia, Vol 3, Iss 1, Pp 1-6 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Psychiatry RC435-571
spellingShingle	Psychiatry RC435-571 Srihari Gopal Haiyan Xu Kelly McQuarrie Adam Savitz Isaac Nuamah Kimberly Woodruff Maju Mathews Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
description	Drug formulation: Easing the toll of caregiving Switching from oral to long-acting injectable antipsychotic medication improves overall caregiver burden. The physical, emotional and financial toll of providing care for patients with schizophrenia is often underestimated. Poor adherence to conventional oral antipsychotics is a major cause of symptomatic relapse in patients and of stress for carers. Srihari Gopal and colleagues at Janssen Pharmaceuticals have pooled data from two large studies involving 1498 caregivers across 27 countries. They found that administration of either 1- or 3-monthly long-acting injectable antipsychotics not only eased the burden of daily dosing and patient compliance, but also had a positive impact on the stress conditions of caregivers. Using the Involvement Evaluation Questionnaire to measure caregiver burden, the authors showed that the switch in drug formulation decreased the need to urge patients to self-care and the hours spent caregiving.
format	article
author	Srihari Gopal Haiyan Xu Kelly McQuarrie Adam Savitz Isaac Nuamah Kimberly Woodruff Maju Mathews
author_facet	Srihari Gopal Haiyan Xu Kelly McQuarrie Adam Savitz Isaac Nuamah Kimberly Woodruff Maju Mathews
author_sort	Srihari Gopal
title	Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
title_short	Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
title_full	Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
title_fullStr	Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
title_full_unstemmed	Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
title_sort	caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/174df3333f1542aba31699e1d40b0a99
work_keys_str_mv	AT sriharigopal caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT haiyanxu caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT kellymcquarrie caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT adamsavitz caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT isaacnuamah caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT kimberlywoodruff caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies AT majumathews caregiverburdeninschizophreniafollowingpaliperidonepalmitatelongactinginjectablestreatmentpooledanalysisoftwodoubleblindrandomizedphasethreestudies
_version_	1718387433002762240

Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies

Ejemplares similares