CDK6 inhibits white to beige fat transition by suppressing RUNX1

Beige adipocytes can arise from transdifferentiation of mature white adipocytes. Here the authors identify CDK6 as a key molecule involved in the white-to-beige adipocyte transdifferentiation and, therefore, as a regulator of organismal energy homeostasis in mice.

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Autores principales: Xiaoli Hou, Yongzhao Zhang, Wei Li, Alexander J. Hu, Chi Luo, Wenhui Zhou, Jamie K. Hu, Stefano G. Daniele, Jinfeng Wang, Jinghao Sheng, Yongsheng Fan, Andrew S. Greenberg, Stephen R. Farmer, Miaofen G. Hu
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/17531b3802bd4bc69983bb653e2b2d97
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spelling oai:doaj.org-article:17531b3802bd4bc69983bb653e2b2d972021-12-02T16:56:39ZCDK6 inhibits white to beige fat transition by suppressing RUNX110.1038/s41467-018-03451-12041-1723https://doaj.org/article/17531b3802bd4bc69983bb653e2b2d972018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03451-1https://doaj.org/toc/2041-1723Beige adipocytes can arise from transdifferentiation of mature white adipocytes. Here the authors identify CDK6 as a key molecule involved in the white-to-beige adipocyte transdifferentiation and, therefore, as a regulator of organismal energy homeostasis in mice.Xiaoli HouYongzhao ZhangWei LiAlexander J. HuChi LuoWenhui ZhouJamie K. HuStefano G. DanieleJinfeng WangJinghao ShengYongsheng FanAndrew S. GreenbergStephen R. FarmerMiaofen G. HuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiaoli Hou
Yongzhao Zhang
Wei Li
Alexander J. Hu
Chi Luo
Wenhui Zhou
Jamie K. Hu
Stefano G. Daniele
Jinfeng Wang
Jinghao Sheng
Yongsheng Fan
Andrew S. Greenberg
Stephen R. Farmer
Miaofen G. Hu
CDK6 inhibits white to beige fat transition by suppressing RUNX1
description Beige adipocytes can arise from transdifferentiation of mature white adipocytes. Here the authors identify CDK6 as a key molecule involved in the white-to-beige adipocyte transdifferentiation and, therefore, as a regulator of organismal energy homeostasis in mice.
format article
author Xiaoli Hou
Yongzhao Zhang
Wei Li
Alexander J. Hu
Chi Luo
Wenhui Zhou
Jamie K. Hu
Stefano G. Daniele
Jinfeng Wang
Jinghao Sheng
Yongsheng Fan
Andrew S. Greenberg
Stephen R. Farmer
Miaofen G. Hu
author_facet Xiaoli Hou
Yongzhao Zhang
Wei Li
Alexander J. Hu
Chi Luo
Wenhui Zhou
Jamie K. Hu
Stefano G. Daniele
Jinfeng Wang
Jinghao Sheng
Yongsheng Fan
Andrew S. Greenberg
Stephen R. Farmer
Miaofen G. Hu
author_sort Xiaoli Hou
title CDK6 inhibits white to beige fat transition by suppressing RUNX1
title_short CDK6 inhibits white to beige fat transition by suppressing RUNX1
title_full CDK6 inhibits white to beige fat transition by suppressing RUNX1
title_fullStr CDK6 inhibits white to beige fat transition by suppressing RUNX1
title_full_unstemmed CDK6 inhibits white to beige fat transition by suppressing RUNX1
title_sort cdk6 inhibits white to beige fat transition by suppressing runx1
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/17531b3802bd4bc69983bb653e2b2d97
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