Improving Butanol Fermentation To Enter the Advanced Biofuel Market

ABSTRACT 1-Butanol is a large-volume, intermediate chemical with favorable physical and chemical properties for blending with or directly substituting for gasoline. The per-volume value of butanol, as a chemical, is sufficient for investing into the recommercialization of the classical acetone-butan...

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Autor principal: Bryan P. Tracy
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Publicado: American Society for Microbiology 2012
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spelling oai:doaj.org-article:175bd9ef53554a4eb6ca6b46db0db80e2021-11-15T15:39:11ZImproving Butanol Fermentation To Enter the Advanced Biofuel Market10.1128/mBio.00518-122150-7511https://doaj.org/article/175bd9ef53554a4eb6ca6b46db0db80e2012-12-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00518-12https://doaj.org/toc/2150-7511ABSTRACT 1-Butanol is a large-volume, intermediate chemical with favorable physical and chemical properties for blending with or directly substituting for gasoline. The per-volume value of butanol, as a chemical, is sufficient for investing into the recommercialization of the classical acetone-butanol-ethanol (ABE) (E. M. Green, Curr. Opin. Biotechnol. 22:337–343, 2011) fermentation process. Furthermore, with modest improvements in three areas of the ABE process, operating costs can be sufficiently decreased to make butanol an economically viable advanced biofuel. The three areas of greatest interest are (i) maximizing yields of butanol on any particular substrate, (ii) expanding substrate utilization capabilities of the host microorganism, and (iii) reducing the energy consumption of the overall production process, in particular the separation and purification operations. In their study in the September/October 2012 issue of mBio, Jang et al. [mBio 3(5):e00314-12, 2012] describe a comprehensive study on driving glucose metabolism in Clostridium acetobutylicum to the production of butanol. Moreover, they execute a metabolic engineering strategy to achieve the highest yet reported yields of butanol on glucose.Bryan P. TracyAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 3, Iss 6 (2012)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Bryan P. Tracy
Improving Butanol Fermentation To Enter the Advanced Biofuel Market
description ABSTRACT 1-Butanol is a large-volume, intermediate chemical with favorable physical and chemical properties for blending with or directly substituting for gasoline. The per-volume value of butanol, as a chemical, is sufficient for investing into the recommercialization of the classical acetone-butanol-ethanol (ABE) (E. M. Green, Curr. Opin. Biotechnol. 22:337–343, 2011) fermentation process. Furthermore, with modest improvements in three areas of the ABE process, operating costs can be sufficiently decreased to make butanol an economically viable advanced biofuel. The three areas of greatest interest are (i) maximizing yields of butanol on any particular substrate, (ii) expanding substrate utilization capabilities of the host microorganism, and (iii) reducing the energy consumption of the overall production process, in particular the separation and purification operations. In their study in the September/October 2012 issue of mBio, Jang et al. [mBio 3(5):e00314-12, 2012] describe a comprehensive study on driving glucose metabolism in Clostridium acetobutylicum to the production of butanol. Moreover, they execute a metabolic engineering strategy to achieve the highest yet reported yields of butanol on glucose.
format article
author Bryan P. Tracy
author_facet Bryan P. Tracy
author_sort Bryan P. Tracy
title Improving Butanol Fermentation To Enter the Advanced Biofuel Market
title_short Improving Butanol Fermentation To Enter the Advanced Biofuel Market
title_full Improving Butanol Fermentation To Enter the Advanced Biofuel Market
title_fullStr Improving Butanol Fermentation To Enter the Advanced Biofuel Market
title_full_unstemmed Improving Butanol Fermentation To Enter the Advanced Biofuel Market
title_sort improving butanol fermentation to enter the advanced biofuel market
publisher American Society for Microbiology
publishDate 2012
url https://doaj.org/article/175bd9ef53554a4eb6ca6b46db0db80e
work_keys_str_mv AT bryanptracy improvingbutanolfermentationtoentertheadvancedbiofuelmarket
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