Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam

Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications...

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Autores principales:	Antti Mustonen, Juhani Leijala, Johanna Aronranta, Antero Lassila, Mauri Aalto, Janne Koskimäki
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Psychiatry RC435-571
Acceso en línea:	https://doaj.org/article/175f7f4e40c24626992afd360f636256
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spelling	oai:doaj.org-article:175f7f4e40c24626992afd360f6362562021-11-15T01:19:49ZWithdrawal from Long-Term Use of Unusually High-Dose Oxazepam2090-683810.1155/2021/2140723https://doaj.org/article/175f7f4e40c24626992afd360f6362562021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2140723https://doaj.org/toc/2090-6838Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases.Antti MustonenJuhani LeijalaJohanna AronrantaAntero LassilaMauri AaltoJanne KoskimäkiHindawi LimitedarticlePsychiatryRC435-571ENCase Reports in Psychiatry, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Psychiatry RC435-571
spellingShingle	Psychiatry RC435-571 Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
description	Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases.
format	article
author	Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki
author_facet	Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki
author_sort	Antti Mustonen
title	Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
title_short	Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
title_full	Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
title_fullStr	Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
title_full_unstemmed	Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
title_sort	withdrawal from long-term use of unusually high-dose oxazepam
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/175f7f4e40c24626992afd360f636256
work_keys_str_mv	AT anttimustonen withdrawalfromlongtermuseofunusuallyhighdoseoxazepam AT juhanileijala withdrawalfromlongtermuseofunusuallyhighdoseoxazepam AT johannaaronranta withdrawalfromlongtermuseofunusuallyhighdoseoxazepam AT anterolassila withdrawalfromlongtermuseofunusuallyhighdoseoxazepam AT mauriaalto withdrawalfromlongtermuseofunusuallyhighdoseoxazepam AT jannekoskimaki withdrawalfromlongtermuseofunusuallyhighdoseoxazepam
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Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam

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