Anti-Apoptotic Effect of Flavokawain A on Ochratoxin-A-Induced Endothelial Cell Injury by Attenuation of Oxidative Stress via PI3K/AKT-Mediated Nrf2 Signaling Cascade

Anti-Apoptotic Effect of Flavokawain A on Ochratoxin-A-Induced Endothelial Cell Injury by Attenuation of Oxidative Stress via PI3K/AKT-Mediated Nrf2 Signaling Cascade

This study investigates the endothelial protective activity of flavokawain A (FKA) against oxidative stress induced by ochratoxin A (OTA), which acts as a mycotoxin, and its primary mechanisms in in vitro models. Reactive oxygen species, in general, regulate oxidative stress that significantly contr...

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Autores principales: Peramaiyan Rajendran, Abdullah M. Alzahrani, Vishnu Priya Veeraraghavan, Emad A. Ahmed
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
flavokawain A
ochratoxin A
oxidative stress
apoptosis
Nrf2
Medicine
R
Acceso en línea:https://doaj.org/article/176880142ab242aab8eeed9abb67e6b3
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