Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators.

In the fission yeast Schizosaccharomyces pombe, genetic evidence suggests that two mediators, Rad22 (the S. pombe Rad52 homolog) and the Swi5-Sfr1 complex, participate in a common pathway of Rhp51 (the S. pombe Rad51 homolog)-mediated homologous recombination (HR) and HR repair. Here, we have demons...

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Main Authors: Yumiko Kurokawa, Yasuto Murayama, Nami Haruta-Takahashi, Itaru Urabe, Hiroshi Iwasaki
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
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Online Access:https://doaj.org/article/176e3a65b51f4eb793868471fab4dc7c
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