The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

The midbody is an organelle present at the bridge connecting two cells at the end of cell division. Here, the authors use mass spectrometry to define the midbody interactome and uncover a role for PP1 phosphatases in microtubule dynamics and regulation of cytokinesis.

Guardado en:
Detalles Bibliográficos
Autores principales: Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/177bc1ea9d354f81bf5e06e1a9578c31
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:177bc1ea9d354f81bf5e06e1a9578c31
record_format dspace
spelling oai:doaj.org-article:177bc1ea9d354f81bf5e06e1a9578c312021-12-02T17:01:26ZThe midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis10.1038/s41467-019-12507-92041-1723https://doaj.org/article/177bc1ea9d354f81bf5e06e1a9578c312019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12507-9https://doaj.org/toc/2041-1723The midbody is an organelle present at the bridge connecting two cells at the end of cell division. Here, the authors use mass spectrometry to define the midbody interactome and uncover a role for PP1 phosphatases in microtubule dynamics and regulation of cytokinesis.Luisa CapalboZuni I. BassiMarco GeymonatSofia TodescaLiviu CopoiuAnton J. EnrightGiuliano CallainiMaria Giovanna RiparbelliLu YuJyoti S. ChoudharyEnrico FerreroSally WheatleyMax E. DouglasMasanori MishimaPier Paolo D’AvinoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Luisa Capalbo
Zuni I. Bassi
Marco Geymonat
Sofia Todesca
Liviu Copoiu
Anton J. Enright
Giuliano Callaini
Maria Giovanna Riparbelli
Lu Yu
Jyoti S. Choudhary
Enrico Ferrero
Sally Wheatley
Max E. Douglas
Masanori Mishima
Pier Paolo D’Avino
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
description The midbody is an organelle present at the bridge connecting two cells at the end of cell division. Here, the authors use mass spectrometry to define the midbody interactome and uncover a role for PP1 phosphatases in microtubule dynamics and regulation of cytokinesis.
format article
author Luisa Capalbo
Zuni I. Bassi
Marco Geymonat
Sofia Todesca
Liviu Copoiu
Anton J. Enright
Giuliano Callaini
Maria Giovanna Riparbelli
Lu Yu
Jyoti S. Choudhary
Enrico Ferrero
Sally Wheatley
Max E. Douglas
Masanori Mishima
Pier Paolo D’Avino
author_facet Luisa Capalbo
Zuni I. Bassi
Marco Geymonat
Sofia Todesca
Liviu Copoiu
Anton J. Enright
Giuliano Callaini
Maria Giovanna Riparbelli
Lu Yu
Jyoti S. Choudhary
Enrico Ferrero
Sally Wheatley
Max E. Douglas
Masanori Mishima
Pier Paolo D’Avino
author_sort Luisa Capalbo
title The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
title_short The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
title_full The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
title_fullStr The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
title_full_unstemmed The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
title_sort midbody interactome reveals unexpected roles for pp1 phosphatases in cytokinesis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/177bc1ea9d354f81bf5e06e1a9578c31
work_keys_str_mv AT luisacapalbo themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT zuniibassi themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT marcogeymonat themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT sofiatodesca themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT liviucopoiu themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT antonjenright themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT giulianocallaini themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT mariagiovannariparbelli themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT luyu themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT jyotischoudhary themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT enricoferrero themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT sallywheatley themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT maxedouglas themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT masanorimishima themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT pierpaolodavino themidbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT luisacapalbo midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT zuniibassi midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT marcogeymonat midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT sofiatodesca midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT liviucopoiu midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT antonjenright midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT giulianocallaini midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT mariagiovannariparbelli midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT luyu midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT jyotischoudhary midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT enricoferrero midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT sallywheatley midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT maxedouglas midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT masanorimishima midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
AT pierpaolodavino midbodyinteractomerevealsunexpectedrolesforpp1phosphatasesincytokinesis
_version_ 1718382132413333504

Ejemplares similares