Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface

The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic remodelling of protein opsonins in vivo.

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Autores principales:	Srinivas Abbina, Lily E. Takeuchi, Parambath Anilkumar, Kai Yu, Jason C. Rogalski, Rajesh A. Shenoi, Iren Constantinescu, Jayachandran N. Kizhakkedathu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1781b338e91c42bfbfee966be2fca34b
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spelling	oai:doaj.org-article:1781b338e91c42bfbfee966be2fca34b2021-12-02T16:04:12ZBlood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface10.1038/s41467-020-16772-x2041-1723https://doaj.org/article/1781b338e91c42bfbfee966be2fca34b2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16772-xhttps://doaj.org/toc/2041-1723The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic remodelling of protein opsonins in vivo.Srinivas AbbinaLily E. TakeuchiParambath AnilkumarKai YuJason C. RogalskiRajesh A. ShenoiIren ConstantinescuJayachandran N. KizhakkedathuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Srinivas Abbina Lily E. Takeuchi Parambath Anilkumar Kai Yu Jason C. Rogalski Rajesh A. Shenoi Iren Constantinescu Jayachandran N. Kizhakkedathu Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
description	The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic remodelling of protein opsonins in vivo.
format	article
author	Srinivas Abbina Lily E. Takeuchi Parambath Anilkumar Kai Yu Jason C. Rogalski Rajesh A. Shenoi Iren Constantinescu Jayachandran N. Kizhakkedathu
author_facet	Srinivas Abbina Lily E. Takeuchi Parambath Anilkumar Kai Yu Jason C. Rogalski Rajesh A. Shenoi Iren Constantinescu Jayachandran N. Kizhakkedathu
author_sort	Srinivas Abbina
title	Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
title_short	Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
title_full	Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
title_fullStr	Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
title_full_unstemmed	Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
title_sort	blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1781b338e91c42bfbfee966be2fca34b
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Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface

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