Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface

The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic remodelling of protein opsonins in vivo.

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Autores principales: Srinivas Abbina, Lily E. Takeuchi, Parambath Anilkumar, Kai Yu, Jason C. Rogalski, Rajesh A. Shenoi, Iren Constantinescu, Jayachandran N. Kizhakkedathu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1781b338e91c42bfbfee966be2fca34b
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