SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis

ABSTRACT The effect of the rapid accumulation of nonsynonymous mutations on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not yet known. The 3a protein is unique to SARS-CoV and is essential for disease pathogenesis. Our study aimed at determining the nonsynonym...

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Bibliographic Details
Main Authors: Elio Issa, Georgi Merhi, Balig Panossian, Tamara Salloum, Sima Tokajian
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/17820af1c1a44c23afe10b4f64c46b29
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